Depressive disorders and immunity: 20 years of progress and discovery.

By Michael R. Irwin, Andrew H. Miller. Brain, behavior, and immunity, 2007

687 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Biological Psychiatry, Social Psychology

View Paper: https://www.semanticscholar.org/paper/a4605c49de8682a32c802f8349093ca63627d2f0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

In Biological Psychiatry

In Social Psychology

Citations in the corpus

Early-Life Programming of Later-Life Brain and Behavior: A Critical Role for the Immune System (2009, background): “Exaggerated expression of CNS cytokines, including IL-1β, has been linked to depression in a large number of studies (Dantzer et al., 2008; Hayley et al., 2005; Irwin and Miller, 2007; Maier and Watkins, 1998; Pollak and Yirmiya, 2002).”
Cytokines and their relationship to the symptoms and outcome of cancer (2008, background): “In general, depressed patients have an activated HPA axis, increased levels of cortisol and increased circulating levels of several pro-inflammatory cytokines, which can further stimulate the HPA axis and cortisol productio”
Immune System to Brain Signaling: Neuropsychopharmacological Implications (2011, background): “…be involved in depression (Wong et al., 2008), few studies have directly examined the relative expression and function of relevant T cell subsets beyond the characterization of CD4+ and CD8+ T cell phenotypes and mitogen-induced T cell proliferation (Zorrilla et al., 2001; Irwin and Miller, 2007).”
From inflammation to sickness and depression: when the immune system subjugates the brain (2008, background): “Despite its originality, especially at a time when depression was thought to be associated with decreased rather than increased immunit”
Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior (2012, background): “These data came as somewhat of a surprise, because they occurred in the context of a pre-existing literature on the immune system in depression, which was dominated by reports of decreased cellular (lymphocyte) responses and reduced natural killer-cell activity (Irwin and Miller, 2007).”
Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder (2015, background): “Similarly, chronic diseases, severity of depressive symptoms and comorbid psychiatric disorders may affect the magnitude of the associations between inflammation and major depression (Hiles et al., 2012b; Howren et al., 2009; Irwin and Miller, 2007; Stuart and Baune, 2012; Van der Kooy et al., 2007)”
Why Sleep Is Important for Health: A Psychoneuroimmunology Perspective (2014, background): “Additionally, sleep disturbance appears to be a critical pathway by which psychological stress and major depression lead to a reduction in NK activity (Cover & Irwin 1994, Irwin & Miller 2007). www.annualreviews.org • Sleep, Immunity, and Health 155 A nn u.”
Religion, Spirituality, and Health: The Research and Clinical Implications (2012, background): “Because stress hormones (cortisol, epinephrine, and norepinephrine) have a known inﬂuence on immune (and cardiovascular) functions, they are important factors on the pathway between R/S involvement and health [455, 456].”
From Stress to Inflammation and Major Depressive Disorder: A Social Signal Transduction Theory of Depression (2014, background): “As reviewed elsewhere, elevated proinflammatory cytokine levels are not the only indication that inflammation may be a key biological mediator of depression (Irwin & Miller, 2007; Maes, 2011; Zorrilla et al., 2001).”
Inflammation-Associated Depression: From Serotonin to Kynurenine (2010, background): “N IH -PA Author M anuscript N IH -PA Author M anuscript N IH -PA Author M anuscript no consensus as to the best biomarkers to reveal systemic inflammation (Dantzer et al 2008a; Irwin & Miller 2007).”
Evidence for a cytokine model of cognitive function. (2009, background): “, 2004) and in neuropsychiatric disorders, such as depression (Anisman et al., 2008; Capuron and Dantzer, 2003; Dantzer et al., 2008; Irwin and Miller, 2007; Kronfol and Remick, 2000; Raison et al., 2006).”