Gut microorganisms, mammalian metabolism and personalized health care

By Jeremy K. Nicholson, Edward C. Holmes, Ian A. Wilson. Nature Reviews Microbiology, 2005

909 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/c6cdf93eed9e8b4154764d2a77e50668f20d0027

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Citations in the corpus

Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics. (2015, background): “Hypothesis and Data-Driven Science Hand in Hand Personalized medicine has been hyped for many years.(79,80) However, the success of this potentially useful concept to base health and disease assessment on individual molecular data is intrinsically hampered in the area of common metabolic disorders.”
Multivariate Analysis in Metabolomics. (2012, background): “Studies have shown that the microbiome – the sum total of all microbial organisms – of the human gastrointestinal tract has a great impact on individual metabolite profiles, even when genetic variations are minimized [114].”
Diversity of the human gastrointestinal tract microbiota revisited. (2007, background): “Still, the vast majority of authors refer to an expected diversity of about 400–500 species, but in some of the recent reports the number of 1000 gastrointestinal species appears (Noverr and Huffnagle, 2004; Nicholson et al., 2005; Phillips, 2006).”
The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing (2008, background): “mediated by specific microbial populations [17], with impli-”
Carbohydrate metabolism in Bifidobacteria (2011, background): “Research on the gut microbiota composition in humans, as supported by work in gnotobiotic mouse models, has revealed the existence of a mutualistic relationship between humans and the gut microbiota, which acts as a virtual organ to (1) influence maturation of the immune system [76, 90], (2) defend ”
Gut microbiota in health and disease. (2010, neutral): “ent geographic and cultural populations (212).”
Chapter 12: Human Microbiome Analysis (2012, background): “The gut, however, is currently the beststudied human microbiome [119,124,125].”
Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns (2010, background): “Mutualistic relationships with intestinal bacteria are known to influence energy balance (12–15), metabolism of xenobiotics (16, 17), pathogen colonization resistance (18, 19), and the maturation of the intestine and the immune system (20, 21), and similarly important roles are likely played by the ”
Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers (2011, background): “The ISME Journal The ISME Journal health status of the intestinal tract and the whole body (Nicholson et al., 2005).”
Resistant Starches Types 2 and 4 Have Differential Effects on the Composition of the Fecal Microbiota in Human Subjects (2010, background): “The gastrointestinal microbiota is of profound importance for the human host, affecting its metabolism, immune functions, and physiology with implications to health [1,2].”
Impact of the gut microbiota on inflammation, obesity, and metabolic disease (2016, background): “The study of the metabolic, signaling, and immune interactions between gut microbes and the host, and how these interactions modulate host brain, muscle, liver and gut functions, has raised the concept of therapeutic microbial manipulation to combat or prevent diseases [4, 10].”