Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers

By Tingting Wang, G. Cai, Yunping Qiu, N. Fei, Menghui Zhang, Xiaoyan Pang, W. Jia, S. Cai, Liping Zhao. The ISME Journal, 2011

1,187 citations recorded by the source corpus.

Subfields: Epidemiology, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0024b48155eec44524cc8af982ff9e0389b1bc5b

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Citations in the corpus

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages (2019, background): “This is potentially relevant for human immunopathology since reduced numbers of butyrate-producing bacteria were found in the gut mucosa and in fecal samples from patients with inflammatory bowel disease (IBD) or colon cancer (Frank et al., 2007; Wang et al., 2012).”
Taxonomic Classification of Bacterial 16S rRNA Genes Using Short Sequencing Reads: Evaluation of Effective Study Designs (2013, background): “This lack of consensus is apparent in recent literature, with most current studies focusing on either hypervariable region V3, V4 or V6 [10,28,30–33], with no convergence on a single hypervariable region being chosen.”
The Warburg Effect Dictates the Mechanism of Butyrate Mediated Histone Acetylation and Cell Proliferation (2012, background): “…of butyrate-producing bacteria among the gut microbiota of colorectal cancer patients compared to healthy participants (Balamurugan et al., 2008; Wang et al., 2012), and studies showing an inverse correlation between fecal butyrate levels and tumor size in colorectal cancer (BoutronRuault et…”
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites. (2016, positive): “More specifically, butyrate seems to be related to a protective role based on a significant decrease in the number of butyrate-producing bacteria in the colon of patients with ulcerative colitis and colon cancer (Frank et al., 2007; Wang et al., 2012) and an amelioration of experimental colitis (AOM”
Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer (2017, background): “Indeed, next-generation sequencing methods based on 16s rRNA have revealed an enrichment in proinflammatory bacteria, such as Fusobacterium, which is also overrepresented in other diseases (for example IBD), as well as a lower abundance of butyrate producers, such as protective bifidobacteria [145,1”
The first 1000 cultured species of the human gastrointestinal microbiota (2014, background): “increased in fecal samples of colorectal cancer patients (Wang et al., 2012).”
Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance (2013, result): “Roseburia which are known to be butyrateproducing bacteria, seem to have a protective role, as has been recognized in previous reports [35,36].”
What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases (2019, background): “Daily exercise increases gut microbial diversity (Table 2) with a Firmicutes enrichment microbiota: Clostridiales, Roseburia, Lachnospiraceae, and Erysipelotrichaceae by producing more SCFAs which may increase the expression of tight junction proteins in colon epithelia to heighten the resistance of”