Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

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Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. (2010, neutral): “A fourth cell type, the Paneth cell, also derives from the stem cells but migrates downwards and settles at the crypt base to live for 6–8 weeks (van der Flier and Clevers, 2009).”
The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength (2014, neutral): “Finally, homozygous mutant Lgr6 mice displayed no apparent phenotype (Snippert et al. 2010).”
Wound healing and skin regeneration. (2015, background): “Similarly, Lgr6-positive cells identified in the isthmus area are shown to contribute to reepithelialization (Snippert et al. 2010).”
Wnt/β-catenin signaling and disease. (2012, positive): “Lgr6 similarly marks a rare, primitive stem cell that generates all lineages of the skin (Snippert et al., 2010).”
Wnt/ b -Catenin Signaling, Disease, and Emerging Therapeutic Modalities (2017, background): “Lgr6 similarly marks stem cells in the skin (Füllgrabe et al., 2015; Snippert et al., 2010).”