Chronic Granulomatous Disease: Report on a National Registry of 368 Patients
By J. Winkelstein, M. Marino, R. Johnston, J. Boyle, J. Curnutte, J. Gallin, H. Malech, S. Holland, H. Ochs, P. Quie and 4 more. Medicine, 2000
1,658 citations recorded by the source corpus.
Subfields: Epidemiology, Immunology, Infectious Diseases
View Paper: https://www.semanticscholar.org/paper/c1742b5b5e152937abebaa27d3edd7b30a2a2c82
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In Epidemiology
In Immunology
- W. Nauseef
- A. Segal
- T. Kuijpers
- J. Orange
- Arturo Zychlinsky
- C. Winterbourn
- K. Griendling
- David I. Brown
Citations in the corpus
- NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology (2021, background): “This flavocytochrome was absent in leukocytes of CGD patients [21,22] and was insensitive to conventional inhibitors of mitochondria and myeloperoxidase [3,16].”
- Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury (2015, background): “Obstructive gastrointestinal and genitourinary granulomas in CGD are usually not caused by infections but by chronic inflammation [135] and often coincide with colonic inflammation reminiscent of Crohn’s disease [127,128,136].”
- Biotechnological Applications of Acetic Acid Bacteria (2008, background): “Patients suffer from recurrent lifethreatening infections with catalase-producing organisms and also develop tissue granulomas (Winkelstein et al., 2000).”
- 2013 IDSA clinical practice guideline for vaccination of the immunocompromised host. (2014, background): “Patients with CGD are not at increased risk for infections with pneumococcus [127, 128], and there is limited data on the risk of invasive pneumococcal infection in patients with other phagocytic cell defects [127, 128].”
- How human neutrophils kill and degrade microbes: an integrated view (2007, background): “The significant morbidity secondary to infection in patients with CGD provides a dramatic demonstration of the importance of the NADPH oxidase for normal host defense (26, 143).”
- Chronic granulomatous disease (2010, background): “Aspergillus is the most common organism isolated (41%) followed by Staphylococcus (11%), Burkholderia cepacia (7%), and Nocardia (6%) [1].”
- How neutrophils kill microbes. (2005, background): “This, coupled with the fact that most CGD patients are able to kill most invading microbes most of the time (8), indicates that killing systems of the neutrophil are highly efficient and multilayered.”