Myeloid-derived suppressor cell heterogeneity and subset definition.

By E. Peranzoni, S. Zilio, Ilaria Marigo, L. Dolcetti, Paola Zanovello, S. Mandruzzato, V. Bronte. Current Opinion in Immunology, 2010

675 citations recorded by the source corpus.

Subfields: Immunology, Neurology

View Paper: https://www.semanticscholar.org/paper/c1570ab329600a235a5f2edc055644fd8cd8cc6c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. D. Gabrilovich
2. A. Mantovani
3. V. Bronte
4. S. Ostrand-Rosenberg
5. C. Garlanda
6. T. Condamine
7. Je-in Youn
8. S. Jaillon

In Neurology

1. D. Gabrilovich
2. V. Bronte
3. A. Mantovani
4. J. Massagué
5. E. Batlle

Citations in the corpus

• Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer. (2015, background): “In addition, neutrophils may play an important part in mediating tumor immune evasion both as immature neutrophils (G-MDSCs) (Peranzoni et al., 2010) and as mature cells (e.g., by attracting T-regulatory cells C to the tumor bed, recently reviewed in Sionov et al., 2014).”
• Monocyte recruitment during infection and inflammation (2011, background): “In addition, monocytes can be recruited to tumour sites and can inhibit tumour-specific immune defence mechanism”
• Tumor-derived granulocyte-macrophage colony stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer (2012, background): “…system by targeting Gr-1 + CD11b + cells or the cytokines that regulate their differentiation. comprised of precursors to macrophages, dendritic cells, and granulocytes at earlier stages of differentiation (Gabrilovich and Nagaraj, 2009; Ostrand-Rosenberg and Sinha, 2009; Peranzoni et al., 2010).”
• Targeting interleukin-6 in inflammatory autoimmune diseases and cancers. (2014, background): “IL-6 plays a role in differentiation of myeloid-derived suppressor cells (MDSCs) which may be important for intra-tumoral inflammatory processes (Gabrilovich & Nagaraj, 2009; Peranzoni et al., 2010).”
• Tumor-associated neutrophils: friend or foe? (2012, neutral): “important role in cancer biology [2,3,5-8].”
• Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types? (2018, background): “For this reason, they were named myeloidderived suppressor cells (MDSC) (Peranzoni et al., 2010).”
• Tumor associated macrophages and neutrophils in cancer. (2013, background): “In addition to macrophages and neutrophils, cancer growth is accompanied by the expansion of a heterogeneous population of immunosuppressive cells functionally defined as myeloidderived suppressor cells (MDSC) (Gabrilovich et al. 2007; Peranzoni et al. 2010).”
• Coordinated regulation of myeloid cells by tumours (2012, background): “MDSCs were originally identified in tumour-bearing mice as cells that co-express CD11b and GR1; however, their phenotype in cancer is rather divers”
• HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment (2010, background): “MDSC is a large group of myeloid cells consisting of immature macrophages (M), granulocytes, and DCs, as well as myeloid cells at earlier stages of differentiation (Sica and Bronte, 2007; Talmadge, 2007; Gabrilovich and Nagaraj, 2009; Peranzoni et al., 2010).”