The Pleiotropic Two-Component Regulatory System PhoP-PhoQ

By E. Groisman. Journal of Bacteriology, 2001

883 citations recorded by the source corpus.

Subfields: Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/c0428b9c523f62fe07ff357bf0fd34d491c0608a

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In Nutrition and Dietetics

1. P. Kivistik
2. I. Smith
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4. S. Eriksson
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Citations in the corpus

• Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms (2008, background): “As an intracellular pathogen, the PhoPQ system of Salmonella typhimurium is activated by limiting magnesium in vitro and phoP-regulated genes are also induced after invasion of macrophages and epithelial cells [65].”
• Antimicrobial Resistance and Virulence: a Successful or Deleterious Association in the Bacterial World? (2013, background): “PhoP-PhoQ.”
• Mechanisms of Antimicrobial Peptide Action and Resistance (2003, background): “For example, significant fluctuations in Mg(2) or Ca(2) concentrations (intracellular or transcellular) induced by antimicrobial peptides have been suggested to activate the Salmonella PhoP/PhoQ locus (Groisman, 2001).”
• ColR-ColS signalling system and transposition of Tn4652 in the adaptation of Pseudomonas putida (2010, background): “Binding of cations stabilises the conformation of PhoQ that is unfavourable for the activation of the PhoP and leads to the repression of PhoPregulated genes (Groisman, 2001).”
• Polymyxins: Antibacterial Activity, Susceptibility Testing, and Resistance Mechanisms Encoded by Plasmids or Chromosomes (2017, background): “caused by acidic pH or some virulence factors (126, 127).”
• Role of Nonhost Environments in the Lifestyles of Salmonella and Escherichia coli (2003, background): “coli contain the constitutive Mg(2) transporter CorA (50), the low-Mg(2) -induced Mg(2) transporter MgtA (11, 62, 95), and the Mg(2) responding PhoP-PhoQ two-component regulatory system (38).”
• Mycobacterium tuberculosis Pathogenesis and Molecular Determinants of Virulence (2003, background): “The Salmonella MgtC is a transporter involved in Mg(2) uptake (195) and is essential for this pathogen to grow in low-Mg(2) media and in macrophages, indicating that this environment is limiting for this divalent cation (117).”
• Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica (2002, methodology): “, 2000), phoPQ (Groisman et al., 1997; Groisman, 2001) and pgtE genes (Guina et al.”