Antimicrobial Resistance and Virulence: a Successful or Deleterious Association in the Bacterial World?

By A. Beceiro, M. Tomás, G. Bou. Clinical Microbiology Reviews, 2013

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VFDB 2022: a general classification scheme for bacterial virulence factors (2021, background): “AcrAB of Klebsiella and MtrCDE of Neisseria) to provide resistance to hostile molecules, so as to provide competitive advantages and contribute to bacterial virulence (23).”
Antibiotic resistance: a rundown of a global crisis (2018, background): “However, some are known pathogens which cause infection; these are competent enough to colonize, invade, and harm the host tissue.(50) Pathogenicity is the ability of a bacterium to cause disease, and a pathogen carries a number of factors that facilitate the bacterium to increase their degree of pa”
An overview of the antimicrobial resistance mechanisms of bacteria (2018, background): “Resistance is mediated through acquisition of van genes which results in changes in the structure of peptidoglycan precursors that cause a decrease in the binding ability of vancomycin [21,40].”
Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options (2017, background): “However, no general mechanisms have been proposed (Beceiro et al., 2013).”
Antimicrobial resistance: A global emerging threat to public health systems (2017, background): “Recent studies have found that antibiotic resistance and the different genetic mechanisms (e.g., co-selection and compensatory mutations) might affect the bacterial virulence and fitness (Willems et al., 2011; Beceiro et al., 2013).”