Lipid Rafts and Caveolae as Portals for Endocytosis: New Insights and Common Mechanisms

By Robert G. Parton, A. A. Richards. Traffic : the International Journal of Intracellular Transport, 2003

642 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/bea1f8e42bf41961eb5efcf4460aa97c5ca69309

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. S. Keller
2. Berislav Zlokovic
3. Jeffrey L. Wrana
4. G. Nicolson
5. C. Roy
6. S. Veatch
7. R. Pagano
8. S. Mayor

In Molecular Biology

1. S. Keller
2. Berislav Zlokovic
3. Jeffrey L. Wrana
4. G. Nicolson
5. C. Roy
6. S. Veatch
7. Qiang Zhou
8. X. Bai

Citations in the corpus

• Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling (2005, background): “These internalization routes are not well characterized, but they are exquisitely sensitive to cholesterol depletio”
• The Fluid-Mosaic Model of Membrane Structure: still relevant to understanding the structure, function and dynamics of biological membranes after more than 40 years. (2014, background): “plasma membrane lipid rafts to constitute functional, dynamic submicro- or nano-sized domains (b300 nm, most ~10–200 nm) that are characterized by the enrichments of cholesterol and sphingolipids [18,63,64,67–69,207–221].”
• Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. (2013, neutral): “, 2008) and signal transduction (Lisanti et al., 1994; Parton and Richards, 2003).”
• A class of membrane proteins shaping the tubular endoplasmic reticulum. (2006, neutral): “The reticulons and DP1/Yop1pmay be similar to caveolin, an integral membrane protein that forms oligomers and is abundant in and required for the formation of curved invaginations of the plasma membrane, called caveoli (for review, see Parton and Richards, 2003).”
• Virus Entry: Open Sesame (2006, neutral): “…often leads to activation of tyrosine kinases on the cytosolic side may be related to the fact that the GPIanchored proteins and gangliosides become lipid-raft associated when clustered (Coyne and Bergelson, 2006; Parton, 1994; Parton and Richards, 2003; Pelkmans et al., 2002; Sharma et al., 2004).”
• Seeing spots: complex phase behavior in simple membranes. (2005, background): “For example, line tension could be used to drive endocytosis [94] and differences in membrane thickness could result in sorting of membrane proteins [95].”
• The blood-brain barrier in health and chronic neurodegenerative disorders. (2008, positive): “Recent studies have shown that pericytes are contractile cells which regulate brain capillary blood flow through contraction and relaxation (Peppiatt et al., 2006).”
• Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells (2006, background): “Budding of caveolae from the cell surface provides one mechanism for clathrin-independent endocytosi”
• Cellular Internalization of Exosomes Occurs Through Phagocytosis (2010, background): “Role of Clathrin and Caveolin-1 in exosomes uptake Caveolin1 and clathrin, which are involved in the early steps of cellular internalization (48,49), were also examined.”