Retrograde neuronal tracing with a deletion-mutant rabies virus

By Ian R. Wickersham, S. Finke, K. Conzelmann, Edward M. Callaway. 2007

648 citations recorded by the source corpus.

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Citations in the corpus

The Development and Application of Optogenetics (2011, methodology): “A noteworthy method pioneered by the Callaway group (Wickersham et al. 2007a,b) using a glycoprotein-deficient pseudotyped rabies virus is yet another technique for monosynaptic circuit tracing.”
Genetic dissection of neural circuits. (2008, methodology): “Using thismethod it is possible to label neurons that are presynaptic to a single parent cell (Wickersham et al., 2007b).”
A Neural Circuit for Gut-Induced Reward. (2018, neutral): “To assess the cell-type specificity of parabrachio-nigral targets, we transfected the SNc of both DAT-ires-Cre and VGat-ires-Cre mice with the Cre-inducible, retrograde pseudotyped monosynaptic rabies virus SADΔG-GFP (Figure 4L, Wickersham et al., 2007).”
Neural networks and neuroscience-inspired computer vision. (2014, positive): “For instance, viruses now exist that can jump across a single synapse [69], delivering genetically encoded indicators and opsins that enable the activity of neurons that provide input to a given target to be measured and manipulated.”
Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis. (2014, positive): “In addition, anterograde and retrograde neural tracers, when used with the CUBIC protocol, could also provide direct connectivity information at the whole-brain level (Wickersham et al., 2007).”
Reconstruction and Simulation of Neocortical Microcircuitry. (2015, background): “Although labeling with retrograde and anterograde tracers and trans-synaptic viral vectors, imaging with array tomography, and saturated reconstruction with electron microscopy have made it possible to begin mapping preand postsynaptic neurons for individual neocortical neurons (Boyd and Matsubara, ”
Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb (2013, methodology): “This method is based on targeting primary RABV infection to “starter” cells ectopically expressing TVA, an avian receptor for the envelope protein EnvA used for pseudotyping the RABV (10).”
Identification and Classification of Hubs in Brain Networks (2007, background): “Future anatomical data bases enlarging the range of species may be constructed from genetic markers [60], selectively activated viral tracers [61], novel optical imaging techniques [62] or from diffusion imaging of brain tissue [63,64].”