Osteoblasts in prostate cancer metastasis to bone

By C. Logothetis, Sue-Hwa Lin. Nature Reviews. Cancer, 2005

621 citations recorded by the source corpus.

Subfields: Oncology, Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/bdebbd6ab633657f10ed55c9d12cde0f27ada948

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Oncology

1. J. Massagué
2. P. Steeg
3. C. Abate-Shen
4. M. Shen
5. R. DePinho
6. G. Gupta
7. R. Weinberg
8. D. Nguyen

In Pulmonary and Respiratory Medicine

1. J. Massagué
2. P. Steeg
3. E. Hay

In Radiology, Nuclear Medicine and Imaging

1. J. Massagué
2. P. Steeg

Citations in the corpus

• Genetics and biology of prostate cancer (2018, background): “…endothelin 1 (ET-1), adrenomedullin, fibroblast growth factors (FGFs), platelet-derived growth factor (PDGF), and bone morphogenetic proteins (BMPs), can stimulate osteoblast activation to form new bone via paracrine signaling (Logothetis and Lin 2005; Guise et al. 2006; Body et al. 2015).”
• Tumor metastasis: mechanistic insights and clinical challenges (2006, background): “Breast and prostate carcinomas and multiple myeloma mestastasize to bone (reviewed in refs”
• Cancer metastasis: building a framework. (2006, background): “Osteoclasts, derived from the monocytic branch of hematopoiesis, can be differentiated and stimulated through the expression of cytokines, including M-CSF, RANKL, IL-6, IL-8, and IL-11 (Boyle et al., 2003).”
• Molecular genetics of prostate cancer: new prospects for old challenges. (2010, background): “Thus, unlike other epithelial tumors that occasionally metastasize to bone, metastatic prostate cancer almost invariably metastasizes to bone, and furthermore displays characteristic osteoblastic rather than osteolytic lesions (Logothetis and Lin 2005).”