β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin

By J. Huelsken, Regina Vogel, B. Erdmann, G. Cotsarelis, W. Birchmeier. 2001

1,409 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Urology

View Paper: https://www.semanticscholar.org/paper/bdb6b22b05a205b1b2fdd9614aa59afdee790e52

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Elaine Fuchs
2. C. Blanpain
3. Hans Clevers
4. Linheng Li
5. C. Jamora
6. T. Xie
7. W. Birchmeier
8. W. Nelson

In Molecular Biology

1. Elaine Fuchs
2. C. Blanpain
3. Hans Clevers
4. Linheng Li
5. W. Birchmeier
6. S. Angers
7. Z. Steinhart
8. T. Xie

In Urology

1. Elaine Fuchs
2. C. Blanpain
3. Hans Clevers
4. Linheng Li
5. Pengfei Lu
6. V. Horsley
7. L. Vallier
8. S. Pauklin

Citations in the corpus

• Intercellular adhesion, signalling and the cytoskeleton (2002, background): “Conditional gene disruption of β-catenin in the epidermis showed defects in cell-fate determinatio”
• Molecular Mechanisms of Vitamin D Action (2012, background): “Along with VDR [91], b-catenin is absolutely required in keratinocytes [92] to permit mammalian hair cycling, and the ligand-independent action of VDR to mediate the hair cycle is thought to involve Wnt signaling in skin stem cells [91, 93].”
• Socializing with the neighbors: stem cells and their niche. (2004, background): “…implicate the pathway in to respond negatively to this signal, as the number of regulating SSCs in the skin epithelium (Gat et al., 1998; osteoblasts increases when their surface Bmp receptor Huelsken et al., 2001), the fly ovary (Song and Xie, 2003), IA is genetically mutated (Zhang et al., 2003).”
• Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly (2003, neutral): “Mice containing loxP sites in the second and sixth introns of the β-catenin gene (Huelsken et al., 2001) were crossed to mice that express the cre gene under the control of CamKII regulatory elements (CamKIIcre) (Xu et al., 2000).”
• Stem cell niche: structure and function. (2005, background): “F or p er so na l u se o nl y. ANRV255-CB21-25 ARI 8 September 2005 17:11 determination (by favoring HF over epidermal cell lineages), and differentiation (Gat et al. 1998, Huelsken et al. 2001, Merrill et al. 2001, Niemann et al. 2002).”
• Deletion of β-catenin impairs T cell development (2003, neutral): “Results Tissue-specific deletion of β-catenin To generate T cells with a deletion of β-catenin, we bred mice bearing a LoxP -flanked gene encoding β-catenin ( Catnb”
• Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. (2005, background): “Huelsken, J., Vogel, R., Brinkmann, V., Erdmann, B., Birchmeier, C., and Birchmeier, W. (2000).”
• Wnt-β-catenin signaling initiates taste papilla development (2007, background): “Wnt-β-catenin signaling is critical for development of a broad range of epithelial appendage”
• Nonclassic actions of vitamin D. (2009, background): “The mechanism by which VDR regulates hair follicle cycling remains unclear, but the alopecia phenotype of the VDR null animal is similar to that seen in animals with mutations in Hr (79, 80) and -catenin (81, 82) that render these proteins transcriptionally inactive.”