Socializing with the neighbors: stem cells and their niche.

By Elaine Fuchs, T. Tumbar, Géraldine Guasch. Cell, 2004

1,865 citations recorded by the source corpus.

Subfields: Urology

View Paper: https://www.semanticscholar.org/paper/dda80445580ce2ce1b4e6d539eacf99b96df50eb

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In Urology

1. Linheng Li
2. Pengfei Lu

Citations in the corpus

• Brain micro-ecologies: neural stem cell niches in the adult mammalian brain (2008, background): “123 follicle and nervous system has revealed common and unique features (figure 1; reviewed in Spradling et al. 2001; Doetsch 2003b; Fuchs et al. 2004; Li & Xie 2005).”
• A perivascular niche for brain tumor stem cells. (2007, background): “Stem cells of various tissues exist within protective niches that are composed of a number of differentiated cell types (Fuchs et al., 2004; Moore and Lemischka, 2006).”
• High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue (2020, positive): “Spatial gene expression heterogeneity plays an essential role in a range of biological, physiological and pathological processes(de Bruin et al., 2014; Fuchs et al., 2004; Yudushkin et al., 2007).”
• Normal stem cells and cancer stem cells: the niche matters. (2006, background): “It is, therefore, reasonable to propose that h-catenin is a key molecule bridging two states of stem cells (58): the arrested state when stem cells are attached to the niche through the cadherin-h-catenin adhesion interaction (21, 59) and the activated state in which h-catenin is nuclearly”
• Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity (2008, background): “When regarding normal stem cells as the paradigm, it seems logical to assume that this is regulated by a niche that provides coordinated signals (21, 22).”
• The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche (2010, background): “The microenvironment, or niche, plays a crucial role in selfrenewal and differentiation of hematopoietic stem cells (HSCs) (Fuchs et al., 2004; Spradling et al., 2001).”
• Extracellular matrix: A dynamic microenvironment for stem cell niche (2014, background): “It was demonstrated that several genes encoding for ECM proteins, such as tenascin-C, collagen VI, collagen XVIII/endostatin, fibulin1 and SPARC, display higher expression levels in mouse bulge cells than in differentiated keratinocytes [20,156].”
• c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. (2004, background): “The balance between self-renewal and differentiation of stem cells is thought to be controlled by interaction of stem cells with their niches (Watt and Hogan 2000; Spradling et al. 2001; Fuchs et al. 2004).”