Deletion of β-catenin impairs T cell development

By Youyuan Xu, D. Banerjee, J. Huelsken, W. Birchmeier, J. Sen. Nature Immunology, 2003

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Differentiation and persistence of memory CD8+ T cells depend on T cell factor 1 (2010, background): “However, several studies demonstrated that TCF-1-b-catenin pathway is operative in naive or activated T cells (Jeannet et al., 2008; Wu et al., 2007) and can be modulated by TCR signaling (Xu et al., 2003).”
Wnt signalling in stem cells and cancer (2005, result): “These data are difficult to reconcile with the previous literature that suggests that β-catenin and other elements of the Wnt signalling pathway are required for T-cell developmen”