Chimerism of the transplanted heart.

By G. Spangrude, B. Torok-Storb, M. Little. New England Journal of Medicine, 2002

661 citations recorded by the source corpus.

Subfields: Surgery

View Paper: https://www.semanticscholar.org/paper/bd58551453e0053487c89cc804768ac430853b43

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In Surgery

1. Charles E. Murry
2. Li Chai
3. Diane S. Krause
4. Erica L Herzog
5. Nikolaos G. Frangogiannis
6. G. Keller

Citations in the corpus

• Plasticity of marrow-derived stem cells. (2003, positive): “In humans, after orthotopic transplantation of female hearts into males, up to 15% of cardiac myocytes can be donor derived.(40) Two recent Phase I studies have shown the safety of injecting autologous BM cells into the human heart post-infarct.”
• Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts (2003, background): “and the trafficking of bone marrow–derived stem cells (BMCs) to the myocardium for repair and angiogenesi”
• Adult cardiac stem cells are multipotent and support myocardial regeneration. (2003, positive): “Summary In cases of sex-mismatched cardiac transplants in humans, the female hearts in the male hosts had a signifThe notion of the adult heart as terminally differentiated organ without self-renewal potential has been icant number of Y positive myocytes and coronary vessels (Quaini et al., 2002).”
• Characterization and Enrichment of Cardiomyocytes Derived From Human Embryonic Stem Cells (2002, background): “markers by the differentiated cells, and (3) appropriate”
• Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts (2004, background): “Furthermore, transplanted human hearts contain myocytes derived from extra-cardiac progenitor cell”
• The Oxygen Rich Postnatal Environment Induces Cardiomyocyte Cell Cycle Arrest Through DNA Damage Response (2014, positive): “…the adult heart to regenerate lost or damaged myocardium, and although limited myocyte turnover does occur in the adult heart, it is insufficient for restoration of contractile dysfunction (Bergmann et al., 2009; Hsieh et al., 2007; Laflamme et al., 2002; Nadal-Ginard, 2001; Quaini et al., 2002).”
• Repair of Infarcted Myocardium by Autologous Intracoronary Mononuclear Bone Marrow Cell Transplantation in Humans (2002, background): “(3) Another important variable is the inflammatory response in MI, which seems to be a superbly orchestrated interaction of cells, cytokines, growth factors and extracellular matrix proteins mediating myocardial repair.”