Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
By Charles E. Murry, M. Soonpaa, H. Reinecke, H. Nakajima, H. Nakajima, M. Rubart, K. Pasumarthi, J. Virag, S. Bartelmez, Veronica Poppa and 4 more. Nature, 2004
2,284 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology, Surgery
View Paper: https://www.semanticscholar.org/paper/a147e82e17c43ca9747af2a77deebcbbce0aa9f4
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Citations in the corpus
- Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury. (2007, background): “Very-low-level organ engraftment of circulating bone marrow-derived stem cells has been shown (25, 26) but was not corroborated by others (6, 22).”
- Ischemia/Reperfusion (2016, neutral): “cells into cardiac myocytes and vascular cells, other studies failed to demonstrate such plasticity (42, 577).”
- Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. (2005, background): “Although some recent studies raised controversy regarding the transdifferentiation potential of HSCs (12, 13), another recent study still claimed this potential (39).”
- Matrix elasticity directs stem cell lineage specification. (2006, background): “Efficacy appears uncertain or mixed (Murry et al., 2004), and recent findings have raised the possibility that the injured microenvironment loses compliance with fibrotic scarring, producing a noninducing environment (Berry et al., 2006) that, as we show here, stem cells cannot sufficiently remodel.”
- Unchain my heart: the scientific foundations of cardiac repair. (2005, methodology): “In one example (34), the peri-infarct zone was injected with Lin–Kit+ cells from bone marrow of transgenic mice bearing an”