Use and abuse of HOMA modeling.

By T. M. Wallace, J. Levy, D. Matthews. Diabetes Care, 2004

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Brain-derived neurotrophic factor (BDNF) and type 2 diabetes (2007, background): “uk/), since the original HOMA [21] tends to overestimate insulin resistance [22].”
Overproduction of large VLDL particles is driven by increased liver fat content in man (2006, methodology): “The HOMA-IR (homeostasis model assessment for insulin resistance) was calculated from the fasting glucose and serum insulin concentrations as fasting insulin (mU/l)×fasting glucose (mmol/l)/22.5 [ 25 ].”
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk (2009, methodology): “HOMA-IR and HOMA-B was calculated using the HOMA2-calculato”
Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. (2008, methodology): “HOMA or log (HOMA) is used extensively in large epidemiological studies, prospective clinical trials, and clinical research studies (29, 47, 100).”