Dietary n-6 and n-3 polyunsaturated fatty acids: from biochemistry to clinical implications in cardiovascular prevention.

By G. Russo. Biochemical Pharmacology, 2009

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Health Implications of High Dietary Omega-6 Polyunsaturated Fatty Acids (2012, background): “As an example, in patients with IBD, the colonic mucosa contains 3- to 7-fold higher counts of cells expressing the 5-LOX pathway, thus increasing the tissue synthesis of LTB4 [53].”
Meat nutritional composition and nutritive role in the human diet. (2013, background): “However meat can contribute up to 20% of long chain omega 3 polynsaturated fatty acid intake (Russo, 2009).”
Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance - A review. (2018, background): “The cardioprotective effect of n-3 FAs has been reviewed and it is suggested that n-6 FAs, total energy, and fats should be individually considered for the general public to comply with dietary recommendations for PUFAs [32].”
Seasonal variations of total lipids, fatty acid composition, and fucoxanthin contents of Sargassum horneri (Turner) and Cystoseira hakodatensis (Yendo) from the northern seashore of Japan (2012, background): “Intake of these long-chain PUFAs causes significant biochemical and physiological changes in the body and then lowers the risk of cardiovascular disease (Givens and Gibbs 2008; Harris et al. 2008; Leaf et al. 2008; Tziomalos et al. 2008; Allayee et al. 2009; Russo 2010).”