Immune infiltration in human tumors: a prognostic factor that should not be ignored

By Franck Pagès, Jérôme Galon, M. Dieu-Nosjean, E. Tartour, C. Sautès-Fridman, W. Fridman. Oncogene, 2010

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Cancer classification using the Immunoscore: a worldwide task force (2012, background): “prognostic information and facilitate clinical decisionmaking regarding the need for systemic therapy [6,23].”
Hallmarks of cancer: the next generation. (2011, positive): “For example, patients with colon and ovarian tumors that are heavily infiltrated with CTLs and NK cells have a better prognosis than those that lack such abundant killer lymphocytes (Pagès et al., 2010; Nelson, 2008); the case for other cancers is suggestive but less compelling and is the subject of”
Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours (2013, background): “Thus, general characteristics emerge in which cytotoxic T cells, memory T cells and TH1 cells are associated with prolonged survival [35,57,58].”