The application of biofilm science to the study and control of chronic bacterial infections.

By W. Costerton, R. Veeh, M. Shirtliff, M. Pasmore, C. Post, G. Ehrlich. Journal of Clinical Investigation, 2003

811 citations recorded by the source corpus.

Subfields: Endocrinology, Molecular Biology, Periodontics

View Paper: https://www.semanticscholar.org/paper/b585956a30185861c8bb2c07e1d3bb3d51f1c26a

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Citations in the corpus

agr-Mediated Dispersal of Staphylococcus aureus Biofilms (2008, neutral): “elitis, and indwelling medical device infections [3,33].”
Bacterial Extracellular Polysaccharides Involved in Biofilm Formation (2009, background): “These important characteristics have resulted in biofilm science and biofilm engineering emerging as intensively developing areas of research [13].”
Spatial Organization and Composition of the Mucosal Flora in Patients with Inflammatory Bowel Disease (2005, background): “These include periodontal disease, endocarditis, chronic obstructive lung disease, and foreign body-related infections (6, 7).”
The Role of Inflammation and Infection in Preterm Birth (2007, background): “This unique partnership between vaginal tissues and species-specific strains of lactobacilli has been considered responsible for enabling internal fertilization in the evolution of mammals from amphibians.(135) In addition to the low pH, some strains of lactobacilli also produce antimicrobial produc”
Periodontitis: a polymicrobial disruption of host homeostasis (2010, background): “In this respect, biofilms mimic tissues, as individual microorganisms contribute to the structure and function of the biofilm communit”
Identification of FleQ from Pseudomonas aeruginosa as a c-di-GMP-responsive transcription factor (2008, background): “Cells of the opportunistic pathogen Pseudomonas aeruginosa form biofilms in a variety of situations including on indwelling medical devices as well as in the lungs of cystic fibrosis patients (Costerton et al., 1999; 2003; Singh et al., 2000; Hoiby, 2002; Yahr and Greenberg, 2004).”
Quorum Sensing and Bacterial Social Interactions in Biofilms (2012, background): “The infections may persist for months or years, resulting in long-term suffering and tissue damage [1,2].”
The fetal inflammatory response syndrome. (2007, background): “This unique partnership between vaginal tissues and species-specific strain of lactobacilli has been considered responsible for enabling internal fertilization in the evolution of mammals from amphibians.(48) In addition to the low pH, some strains of lactobacilli also produce antimicrobial products”
Antibiotic resistance of bacterial biofilms. (2010, background): “Introduction 59 Biofilm growing bacteria cause chronic infections (1) which are characterized by 60 persisting inflammation and tissue damage (2).”
On the causes of persistent apical periodontitis: a review. (2006, background): “…canal system (Hess 1921, Perrini & Castagnola 1998) and the organization of the microbes into protected adhesive bioﬁlms (Costerton & Stewart 2000, Costerton et al. 2003) composed of microbial cells embedded in a hydrated exopolysaccharide-complex in micro-colonies (Nair 1987, Nair et al. 2005)…”
Specialized Persister Cells and the Mechanism of Multidrug Tolerance in Escherichia coli (2004, background): “Biofilms are responsible for nearly 65% of all human infections in the West (16).”
Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media. (2006, background): “Increasing evidence suggests that microbial biofilms play a role in chronic human infections.(7,9,10,19,20) Criteria proposed for characterizing biofilm infections include direct examination of an infected tissue revealing pathogenic bacteria in clusters within a matrix attached to a surface, infect”