Excitation-neurogenesis coupling in adult neural stem/progenitor cells.

By Karl Deisseroth, Sheela Singla, H. Toda, Michelle Monje, T. Palmer, R. Malenka. 2004

670 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

In Developmental Neuroscience

Citations in the corpus

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, background): “In simple feedforward architectures, replacement of neurons in this manner accelerates learning considerably because the random connections made by the new neurons are flexible and can therefore participate in various network learning paradigms (for example, neurogenesis allows the network to avoid ”
Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells (2006, background): “However, since neurogenesis is also increased by low pathological levels of electrophysiological activity (Derrick et al. 2000; Deisseroth et al. 2004), it is also possible that signals induced by electrophysiological activity play a role in seizure-induced hippocampal neurogenesis.”
A putative role for neurogenesis in neuro-computational terms: inferences from a hippocampal model. (2009, positive): “Most of them share the view, as do we, that new neurons could be necessary for the hippocampus to adapt to new environmental requests, allowing it to cope in the face of novelty and a growing volume of information (Becker, 2005; Chambers & Conroy, 2007; Chambers, Potenza, Hoffman, & Miranker, 2004; ”
Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis (2011, background): “…with the water maze memory (Becker, 2005; Wiskott et al. , 2006), decreased ﬂexibility in acquiring new information (Chambers et al. , 2004; Deisseroth et al. , 2004; Weisz & Argibay, 2009), a qualitatively different way the memories were encoded (Aimone et al. , 2009), or some…”
GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells. (2005, positive): “Depolarization of progenitor cells elicits an elevation of [Ca]i through the activation of voltage-gated calcium channels, as previously reported for both embryonic and adult progenitor cells (LoTurco et al., 1995; Deisseroth et al., 2004).”
Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways (2006, background): “also shown to proliferate following excitatory activity (Deisseroth et al., 2004).”
Excitatory GABA Action Is Essential for Morphological Maturation of Cortical Neurons In Vivo (2007, background): “These in vivo studies have shown that excitatory GABA is involved in neurogenesis, differentiation, morphological maturation, and synapse for- mation of adult newly generated hippocampal granule cells (Deisseroth et al., 2004; Tozuka et al., 2005; Ge et al., 2006).”
Experience dictates stem cell fate in the adult hippocampus. (2011, neutral): “Of particular interest are the multiple observations that neural activity is positively linked to cell division in the adult dentate gyrus (Deisseroth et al., 2004; Tozuka et al., 2005).”
A hypothesis about the role of adult neurogenesis in hippocampal function. (2004, background): “A recent cell culture study has shown that depolarization-mediated calcium influx enhances neuronal differentiation of NPCs, indicating that neurogenesis may be highly influenced not only by the microenvironment provided by extracellular matrix components, cellular neighbors, and secreted factors bu”