Experience dictates stem cell fate in the adult hippocampus.

By A. Dranovsky, Alyssa M. Picchini, T. Moadel, Alexander C. Sisti, Atsushi Yamada, Shioko Kimura, E. Leonardo, R. Hen. 2011

201 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Developmental Neuroscience, Molecular Biology

Citations in the corpus

• Human Hippocampal Neurogenesis Persists throughout Aging (2018, neutral): “…in older age, with preserved Ki-67+ cell numbers, suggest maintained proliferative capacity in healthy aging, perhaps compensating for a smaller QNP pool as an adaptive response to ageassociated social isolation in humans, given that in mice isolation boosted nestin+ cells (Dranovsky et al., 2011).”
• Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding (2016, unknown): “Male ROSA26-CAG-stopflox-ChR2(H134R)-eYFP (Ai32), ROSA26-CAG-stopflox- Arch-GFP (Ai35), ROSA26-CAGstopflox- tDTomato (Ai9) and Nestin-CreERT2 (Dranovsky et al., 2011; Madisen et al., 2012; Madisen et al., 2010)and controls were generated as previously described (on mixed background).”
• Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential (2015, unknown): “Compared to previously reported Nes reporter mouse lines, the transgenic Nes-creERT line used here had a different Nes regulatory sequence directing the expression of creERT (Dranovsky et al., 2011).”
• Modification of hippocampal circuitry by adult neurogenesis (2012, unknown): “Critically, the maintenance and activation of these quiescent population of cells appears to be dynamically regulated by experience and aging (Dranovsky et al., 2011; Encinas et al., 2011).”
• Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors (2015, unknown): “…located in the subgranular zone of the dentate gyrus, and their rates of proliferation, maturation, and survival are impacted by environmental conditions such as age, stress, exercise, and antidepressants (Dranovsky et al, 2011; Gould et al, 1997; Malberg et al, 2000; van Praag et al, 2005).”
• The current state of the neurogenic theory of depression and anxiety. (2015, unknown): “These include repeat restraint stress [13], chronic unpredictable mild stress [14], social defeat stress [15], social isolation [16], and corticosterone administration [4].”
• Differential control of learning and anxiety along the dorso-ventral axis of the dentate gyrus (2013, unknown): “…hippocampus projects to regions implicated in autonomic, neuroendocrine, and motivational responses to emotionally charged stimuli, such as prefrontal cortex (PFC), amygdala, and hypothalamus (Fanselow and Dong, 2010; Gray and McNaughton, 2000; Moser and Moser, 1998; Swanson and Cowan, 1977).”