Different metabolic responses of human brown adipose tissue to activation by cold and insulin.

By Janne Orava, P. Nuutila, Martin E. Lidell, V. Oikonen, T. Noponen, T. Viljanen, M. Scheinin, M. Taittonen, Tarja Niemi, S. Enerbäck and 1 more. Cell Metabolism, 2011

701 citations recorded by the source corpus.

Subfields: Epidemiology, Physiology, Rehabilitation

View Paper: https://www.semanticscholar.org/paper/b3a13b48eabe28ba701c79a60cb22090988f2560

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. L. Sidossis
2. A. Chait
3. S. Kajimura
4. Laura J. den Hartigh

In Physiology

1. S. Kajimura
2. L. Sidossis
3. A. Chait
4. Laura J. den Hartigh
5. B. Spiegelman

In Rehabilitation

1. S. Kajimura
2. L. Sidossis

Citations in the corpus

• Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans. (2012, background): “Of note, a very recent publication demonstrated cold-induced increased blood flow in BAT that was associated with increased energy expenditure (26).”
• Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. (2015, positive): “Cold exposure significantly increases glucose disposal in BAT (110, 113) but not in other tissues.”
• Recruited brown adipose tissue as an antiobesity agent in humans. (2013, positive): “Orava et al. (10) report-ed that increased FDG uptake after cold exposure at 17°C was evident in BAT, but negligible in other tissues, including skeletal muscle.”
• Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease (2020, background): “Glucose disposal through activated BAT occurs by both insulin-dependent and insulin-independent mechanisms (415).”
• Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans (2014, background): “(11) reported that cold exposure (CE) resulted in a 12-fold increase in glucose disposal in BAT, but not in other tissues.”
• Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. (2013, neutral): “01] during mild cold conditions after the cold acclimation period; Table 3), as previously described (26, 27).”