Recruited brown adipose tissue as an antiobesity agent in humans.

By T. Yoneshiro, Sayuri Aita, Mami Matsushita, T. Kayahara, T. Kameya, Y. Kawai, T. Iwanaga, M. Saito. Journal of Clinical Investigation, 2013

907 citations recorded by the source corpus.

Subfields: Physiology, Rehabilitation

View Paper: https://www.semanticscholar.org/paper/62456f5077eaad6282ad70c189b9c6f73ab24a28

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Physiology

1. L. Sidossis
2. S. Kajimura
3. R. Locksley
4. A. Chawla
5. Kong Y. Chen
6. K. Yun
7. R. Zechner
8. Yifu Qiu

In Rehabilitation

1. S. Kajimura
2. L. Sidossis

Citations in the corpus

• Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist (2015, background): “This issue is still unresolved, because these drugswere evaluated prior to the discoveries of functional human BAT and how to measure its metabolic activity via prospective (18)F-fluorodeoxyglucose ((18)F-FDG) PET/CT imaging (van Marken Lichtenbelt et al., 2009; Virtanen et al., 2009; Muzik et al., ”
• What We Talk About When We Talk About Fat (2014, neutral): “2 F) (Chen et al., 2013a; van der Lans et al., 2013; Yoneshiro et al., 2013).”
• Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease (2020, background): “Human brown adipogenesis occurs in response to chronic or repeated cold stimulation, or in response to pharmacologic compounds such as beta adrenergic receptor (β-AR) agonists (68, 69).”
• A switch from white to brown fat increases energy expenditure in cancer-associated cachexia. (2014, background): “, 2009) has been shown recently to significantly affect overall energy balance (Yoneshiro et al., 2013).”
• Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. (2015, positive): “Other studies examined the effect of cold exposure on energy expenditure in individuals with or without detectable BAT and found that BAT-mediated activation increases energy expenditure by 10% to 27% (20, 49, 50, 112).”
• Activated Type 2 Innate Lymphoid Cells regulate Beige Fat Biogenesis (2014, positive): “Moreover, these results are consistent with the previous reports demonstrating that beige fat thermogenesis is stimulated by cold exposure in both mice and humans (Qiu et al., 2014; van der Lans et al., 2013; Yoneshiro et al., 2013).”
• Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans. (2014, background): “While adequate shelter and clothing in modern society have minimized the hazards of cold temperatures, the obesity epidemic has reignited interest into exploring whether harnessing BAT may benefit weight control (Yoneshiro et al., 2013).”