Genome and virulence determinants of high virulence community-acquired MRSA.

By T. Baba, Fumihiko Takeuchi, M. Kuroda, H. Yuzawa, Ken-ichi Aoki, A. Oguchi, Y. Nagai, Natsuko Iwama, Kazuyuki Asano, T. Naimi and 4 more. 2002

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Subfields: Infectious Diseases, Molecular Biology, Public Health, Environmental and Occupational Health

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Citations in the corpus

Antimicrobial resistance: the example of Staphylococcus aureus. (2003, background): “In addition, the presence of virulence genes such as the enterotoxins or the Panton-Valentine leukocidin may also have contributed to patient morbidity in some of the community-acquired infections (30, 31).”
Pathogenicity Islands in Bacterial Pathogenesis (2004, background): “aureus isolates defined six families of PAI and led to the renaming of previously identified PAI to Sa1, Sa2, Sa3, Sa4, Sa , and Sa (9), where stands for “island.”
Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant Staphylococcus aureus Strain and a Biofilm-Producing Methicillin-Resistant Staphylococcus epidermidis Strain (2005, neutral): “aureus N315 (28), Mu50 (28), and MW2 (3) and S.”
Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis (2010, methodology): “Staphylococcus aureus isolate Newman (Duthie and Lorenz, 1952), the colonizing strain BK4645 (Shopsin et al., 2008), and the MRSA S. aureus pulse-field gel electrophoresis types USA400 (strain MW2) (Baba et al., 2002), and USA300s (Kennedy et al., 2008) were used in all experiments as the WT strain ”
Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. (2003, result): “This speculation is further strengthened by a recent report documenting this event in a clinical isolate, and by the fact that SCCmec IV is probably more mobile than other SCCmec alleles.(29,30)”
Genome Sequence of Staphylococcus aureus Strain Newman and Comparative Analysis of Staphylococcal Genomes: Polymorphism and Evolution of Two Major Pathogenicity Islands (2007, methodology): “MRSA strains N315 and Mu50 were the first staphylococcal genomes to be sequenced (18), which were followed by nine additional strains (1, 5, 9, 10, 13, 14).”
Food Poisoning and Staphylococcus aureus Enterotoxins (2010, background): “aureus, often (but not always) encode virulence determinants, are inserted at specific loci in the chromosome and are associated with either intact or remnant DNA recombinases [107,108].”
Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. (2005, background): “The production of PVL may contribute to the unique pathogenicity of CO-MRSA [7, 9, 17, 31].”
Dissemination of New Methicillin-Resistant Staphylococcus aureus Clones in the Community (2002, background): “MW2, a representative C-MRSA strain (2), possessed typical heterogeneous subpopulations of resistant cells, whereas the “truly” (i.”