Dissemination of New Methicillin-Resistant Staphylococcus aureus Clones in the Community

By K. Okuma, K. Iwakawa, J. Turnidge, W. Grubb, J. Bell, F. O'Brien, G. Coombs, J. Pearman, F. Tenover, M. Kapi and 3 more. Journal of Clinical Microbiology, 2002

986 citations recorded by the source corpus.

Subfields: Clinical Biochemistry, Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/503556e4efe7b5c0ddcab952bf088a466ff280af

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Citations in the corpus

Novel Type V Staphylococcal Cassette Chromosome mec Driven by a Novel Cassette Chromosome Recombinase, ccrC (2004, methodology): “Multiple MRSA clones carrying type IV SCCmec were identified in C-MRSA strains from both the United States and Australia by multilocus sequence typing for chromosome genotyping and the PCR technique for SCCmec typing ( 32 ).”
Pathogenesis of methicillin-resistant Staphylococcus aureus infection. (2008, background): “CA-MRSA strains may also have a growth advantage over HAMRSA strains [27, 76].”
The molecular evolution of methicillin-resistant Staphylococcus aureus. (2007, methodology): “[39] showed that CA-MRSA strains represent novel acquisitions of SCCmec type IV in the community.”
Combination of Multiplex PCRs for Staphylococcal Cassette Chromosome mec Type Assignment: Rapid Identification System for mec, ccr, and Major Differences in Junkyard Regions (2006, background): “The results obtained with the M-PCRs were identical to those obtained by traditional methods, which mostly used a set of two primers to identify each gene or different allotypes (7, 10, 18).”
Emergence of community-associated methicillin-resistant Staphylococcus aureus USA300 genotype as a major cause of health care-associated blood stream infections. (2006, background): “Evidence to support this comes in part from the fact that CA-MRSA PFGE types USA300 and USA400 contain the novel SCCmecIV element, which is considerably smaller than SCCmec elements I, II, and III, which are found in traditional HA-MRSA strains [26].”
Antimicrobial resistance: the example of Staphylococcus aureus. (2003, background): “It also appears to occur in a more diverse range of MSSA genetic backgrounds, suggesting that it has been heterologously transferred more readily from other staphylococcal species (41).”
Emergence of Community-Acquired Methicillin-Resistant Staphylococcus aureus USA 300 Clone as the Predominant Cause of Skin and Soft-Tissue Infections (2006, methodology): “For some isolates, we determined SCCmec type by using polymerase chain reaction (PCR)–typing of the mec gene complex as described by Okuma and colleagues (7).”
Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002. (2006, background): “Valentine leukocidin (PVL); and staphylococcal cassette chromosome mec (SCCmec) type I–IV genes [17, 18].”
Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. (2005, background): “These CO-MRSA strains are globally distributed and clonally disseminated [11, 12].”
The evolution of Staphylococcus aureus. (2008, methodology): “Furthermore, the larger clonal diversity of CA-MRSA compared to HA-MRSA suggests that more S. aureus lineages have the ability to become CA-MRSA (Enright et al., 2002; Okuma et al., 2002; Feng et al., 2008; Francois et al., 2008).”
Community-Associated Methicillin-Resistant Staphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic (2010, background): “Abundant molecular evidence supports the hypothesis that CA-MRSA clones have arisen in the community by the horizontal transfer of SCCmec elements and PVL genes, molecular features commonly associated with CA-MRSA isolates as well as perhaps other virulence and resistance factors, to the genomes of ”
Pulsed-Field Gel Electrophoresis Typing of Oxacillin-Resistant Staphylococcus aureus Isolates from the United States: Establishing a National Database (2003, background): “Type I (34 kb) was detected in the first ORSA strain isolated in 1961 in the United Kingdom (strain NCTC 10442) (31); type II (52 kb) was identified in an ORSA strain isolated in 1982 in Japan (strain N315) (30); type III (66 kb) was identified in an MRSA strain isolated in 1985 in New Zealand (stra”
Practice guidelines for the diagnosis and management of skin and soft-tissue infections. (2005, background): “fluoroquinolones, or rifampin; genotypically, they appear not to be related to local hospital strains and to contain type IV SCCmec cassette not typical of hospital isolates [85, 86].”