Pathogenicity Islands in Bacterial Pathogenesis

By H. Schmidt, Michael Hensel. Clinical Microbiology Reviews, 2004

749 citations recorded by the source corpus.

Subfields: Endocrinology, Genetics

View Paper: https://www.semanticscholar.org/paper/a88be7731eeaff58a6c16ad569c90cc14928f46d

How researchers see this paper

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In Endocrinology

1. L. Poirel
2. P. Nordmann
3. Eugene Rosenberg
4. K. Bush
5. J. Pitout
6. David L. Paterson
7. F. Codjoe
8. E. Donkor

In Genetics

1. I. Zilber-Rosenberg
2. Julian Parkhill
3. Eugene Rosenberg
4. P. Nordmann
5. L. Poirel

Citations in the corpus

• Genomic islands: tools of bacterial horizontal gene transfer and evolution (2008, background): “According to their gene content, GEIs are often described as pathogenicity, symbiosis, metabolic, fitness or resistance islands (Dobrindt et al., 2004; Schmidt & Hensel, 2004).”
• Comparative Genomics of Multidrug Resistance in Acinetobacter baumannii (2006, background): “We can safely assume that the mosaic-like structure of the AbaR1 island is the result of successive acquisitions of DNA fragments from different hosts [12], mainly Pseudomonas spp.”
• Interpolated variable order motifs for identification of horizontally acquired DNA: revisiting the Salmonella pathogenicity islands (2006, background): “typhi CT18, raises the following question: What is the minimum size of PAIs or GIs that still maintain their ability to mobilize (integrate-excise)? Usually GIs are expected to be large ( 10kb), distinct chromosomal regions (Schmidt and Hensel, 2004).”
• Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion (2008, background): “ated genes, termed pathogenicity islands (PAI), are important steps for the rapid evolution of pathogenic bacteria from nonpathogenic progenitors (57, 266).”
• The Hologenome Concept: Human, Animal and Plant Microbiota (2014, background): “…many functions necessary for bacteria–host interactions and are found in both pathogens, where they are referred to as pathogenicity islands (Hacker and Kaper 2000; Schmidt and Hensel 2004), and in beneficial symbionts, where they are called symbiosis islands (Finan 2002; MacLean et al. 2007).”
• Genomic islands in pathogenic and environmental microorganisms (2004, background): “Virulence genes that are located on PAIs can be divided into several groups according to the functions they encode: adherence factors, which enable bacteria to attach to host surfaces; siderophores, which ensure sufficient solubilization and uptake of Fe 3+ ions; capsules, which enable avoidance of”