Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells.

By J. Boonstra, J. Post. Gene, 2004

738 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/b0b28e2ac61a5a49873a8ab3e96b3c5b198274de

How researchers see this paper

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In Cancer Research

1. G. Barrera
2. Peng Huang
3. O. Farokhzad
4. Wen-Sheng Wu
5. D. Trachootham
6. Yongqiang Chen
7. S. Gibson
8. M. Azad

In Molecular Biology

1. Kenneth A. Dawson
2. Iseult Lynch
3. D. Trachootham
4. Peng Huang
5. O. Farokhzad
6. J. Alexandre
7. Liying Wang
8. Y. Rojanasakul

In Oncology

1. G. Barrera
2. Peng Huang
3. O. Farokhzad
4. Wen-Sheng Wu
5. Azra Bihorac
6. D. Trachootham

Citations in the corpus

• Cytotoxicity and genotoxicity of silver nanoparticles in human cells. (2009, background): “Some of these electrons occasionally escape from the chain and are accepted by molecular oxygen to form the extremely reactive superoxide anion radical (O2 ), which gets further converted to hydrogen peroxide (H2O2) and in turn may be fully reduced to water or partially reduced to hydroxyl radical (”
• The signaling mechanism of ROS in tumor progression (2007, background): “processes including inhibitor of cyclin dependent kinase p21 for cell cycle arrest [151] and Gadd153 gene for”
• Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? (2009, background): “A moderate increase in ROS can promote cell proliferation and differentiatio”
• Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications (2013, background): “[134] , the impact of ROS on cell cycle depends on the amount and duration of ROS exposure.”
• Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury (2013, background): “Finally, TIMP-2 and IGFBP7 are known to be involved in the response to a wide variety of insults (inflammation, oxidative stress, ultraviolet radiation, drugs, and toxins) [16,23,24].”
• Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy (2012, neutral): “First, ROS play an important role in the initiation and progression of cancer (38, 45, 268, 332).”
• Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity (2013, background): “NP can catalyze the O 2 ∙− generation either by blocking the electron transport chain or accelerating electron transfer to molecular oxygen [54, 55].”
• Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy (2012, background): “A moderate increase in ROS can promote cell proliferation and differentiation [30, 31], whereas excessive amounts of ROS can cause oxidative damage.”