Evolutionary changes in cis and trans gene regulation

By Patricia J. Wittkopp, Belinda K Haerum, Andrew G. Clark. Nature, 2004

892 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/b06fc3a964909cd11b2e72e5c8496a6c814c810d

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Citations in the corpus

Evolutionary genetics of genome merger and doubling in plants. (2008, background): “Allele-specific expression patterns have been observed in a wide range of organisms (60, 116), and the diversity of expression among alleles is thought to be a mechanism underlying heterosis (38).”
The evolutionary significance of cis-regulatory mutations (2007, background): “First, allele-specific measures of transcript abundance indicate that each allele in a diploid organism is transcribed largely independentl”
Molecular mechanisms of heavy metal tolerance and evolution in invertebrates (2009, background): “However, when comparing across species, variation of gene expression mostly appears to reside in cis (Wittkopp et al., 2004).”
THE LOCUS OF EVOLUTION: EVO DEVO AND THE GENETICS OF ADAPTATION (2007, background): “In an elegant study, Wittkopp et al. (2004) examined the contributions of cis- and trans-acting factors to species-level divergence of gene expression in F1 hybrids of Drosophila melanogaster and D. simulans.”
Polyploidy and Crop Improvement (2006, background): “Because much if not most evolutionary change is thought to arise from altered gene expression rather than from protein evolution per se (Wittkopp et al., 2004; Haberer et al., 2004; Stupar and Springer, 2006; Clark et al., 2006), an important dimension to polyploidy may be the increased variance of ”
An evolutionarily conserved mechanism for controlling the efficiency of protein translation. (2010, background): “This is a simple computational resemblance of true species hybridization experiments that are used to tell apart the contribution of cis- and trans-acting factors used in transcription research (Tirosh et al., 2009; Wang et al., 2007; Wittkopp et al., 2004).”
Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence (2011, background): “Studying cis -regulatory evolution Genomic surveys show that cis -regulatory divergence is common between species: using allele-specific expression to detect differences in cis -regulatory activit”
Long-range control of gene expression: emerging mechanisms and disruption in disease. (2005, background): “Elegant evidence for evolutionary change that arises through this pathway comes from Drosophila studies (Wittkopp et al. 2004).”