Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies.

By Mark A Pereira, É. O’Reilly, K. Augustsson, G. Fraser, U. Goldbourt, B. Heitmann, G. Hallmans, P. Knekt, Simin Liu, P. Pietinen and 5 more. Archives of Internal Medicine, 2004

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BACKGROUND Few epidemiologic studies of dietary fiber intake and risk of coronary heart disease have compared fiber types (cereal, fruit, and vegetable) or included sex-specific results. The purpose of this study was to conduct a pooled analysis of dietary fiber and its subtypes and risk of coronary heart disease. METHODS We analyzed the original data from 10 prospective cohort studies from the United States and Europe to estimate the association between dietary fiber intake and the risk of coronary heart disease. RESULTS Over 6 to 10 years of follow-up, 5249 incident total coronary cases and 2011 coronary deaths occurred among 91058 men and 245186 women. After adjustment for demographics, body mass index, and lifestyle factors, each 10-g/d increment of energy-adjusted and measurement error-corrected total dietary fiber was associated with a 14% (relative risk [RR], 0.86; 95% confidence interval [CI], 0.78-0.96) decrease in risk of all coronary events and a 27% (RR, 0.73; 95% CI, 0.61-0.87) decrease in risk of coronary death. For cereal, fruit, and vegetable fiber intake (not error corrected), RRs corresponding to 10-g/d increments were 0.90 (95% CI, 0.77-1.07), 0.84 (95% CI, 0.70-0.99), and 1.00 (95% CI, 0.88-1.13), respectively, for all coronary events and 0.75 (95% CI, 0.63-0.91), 0.70 (95% CI, 0.55-0.89), and 1.00 (95% CI, 0.82-1.23), respectively, for deaths. Results were similar for men and women. CONCLUSION Consumption of dietary fiber from cereals and fruits is inversely associated with risk of coronary heart disease.

Subfields: Nutrition and Dietetics, Plant Science, Public Health, Environmental and Occupational Health

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Citations in the corpus

Glycemic index, glycemic load, and chronic disease risk--a meta-analysis of observational studies. (2008, background): “The findings indicate that the protection offered by low GI or GL diets is similar or higher than that seen for whole grains or fiber on the risk of type 2 diabetes (49), coronary heart disease (50, 51), or colorectal cancer (52).”
Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies. (2009, methodology): “Through literature searches and inquiries with experts in the field, 14 American and European cohort studies were identified and investigators of 11 studies agreed to include their data in the project (6).”
Effects of Dietary Fiber and Its Components on Metabolic Health (2010, background): “added to a diet the mortality risk of CHD decreased by 17–35% [11,4].”
Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid (2016, neutral): “[36,37]”
Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. (2006, result): “The results of these studies have been summarized in previous reviews (4), and an earlier pooled analysis reported an inverse association between intake of fiber from fruit and vegetables and CHD risk (5).”
Chemistry, natural sources, dietary intake and pharmacokinetic properties of ferulic acid: A review. (2008, background): “…a role in an inverse association between cer- eal consumption and the incidence of cardiovascular disorders and diabetes observed by epidemiological studies (de Munter, Hu, Spiegelman, Franz, & van Dam, 2007; Jacobs & Gallaher, 2004; Mozaffarian et al., 2003; Pereira et al., 2004; Qi & Hu, 2007).”
Dietary fibre intake and risk of cardiovascular disease: systematic review and meta-analysis (2013, result): “Our findings are consistent with those of previous reviews but improve on aspects of others that were not systematic reviews of literature, 41 55 56 did not explore fibre from key dietary sources, 57 or did not quantify the dose-response association but reported risks for highest compared with…”