Maturation of Autophagic Vacuoles in Mammalian Cells
By E. Eskelinen. Autophagy, 2005
651 citations recorded by the source corpus.
Subfields: Epidemiology, Physiology
View Paper: https://www.semanticscholar.org/paper/ae4f961635240d2ac0a232d0c8d6584a660fcd29
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Epidemiology
- Ralph A. Nixon
- N. Mizushima
- Beth Levine
- P. Saftig
- E. Eskelinen
- Dun-Sheng Yang
- Saori R. Yoshii
- D. Klionsky
In Physiology
- Ralph A. Nixon
- N. Mizushima
- Beth Levine
- Saori R. Yoshii
- P. Saftig
- Dun-Sheng Yang
- E. Eskelinen
- T. Wyss‐Coray
Citations in the corpus
- Islet amyloid polypeptide, islet amyloid, and diabetes mellitus. (2011, background): “fuses with a lysosome and forms an autolysosome, and degradation begins (14, 90, 104).”
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease (2008, background): “These vesicular profiles, which were strongly cathepsin-positive, correspond to autolysosomes (Lawrence and Brown, 1992; Eskelinen, 2005), which are larger than lysosomes, are relatively electron- translucent, and contain partially digested substrates.”
- Autophagy: a lysosomal degradation pathway with a central role in health and disease. (2009, background): “maturation process including fusion events with multivesicular endosomes and lysosomes [1,23].”
- Monitoring and Measuring Autophagy (2017, background): “Identification of autophagic structures and examples of misinterpretation have been reviewed in detail [12,13,28].”
- Autophagy Failure in Alzheimer's Disease – Locating the Primary Defect (2011, background): “The outer membrane of the autophagosome then fuses with a lysosome or a late endosome to form either an autolysosome or an amphisome, respectively, thereby initiating the digestion of sequestered material by a range of acidic hydrolases (Eskelinen, 2005; Fader and Colombo, 2009; Gordon and Seglen, 1”
- The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. (2008, background): “Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.”