Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

By J. Viala, Catherine Chaput, I. G. Boneca, A. Cardona, S. Girardin, A. Moran, R. Athman, S. Mémet, M. Huerre, A. Coyle and 6 more. Nature Immunology, 2004

1,292 citations recorded by the source corpus.

Subfields: Infectious Diseases, Small Animals, Surgery

View Paper: https://www.semanticscholar.org/paper/ad985f5addc5c0037e3154b41bbd3ff2cc16bc29

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Infectious Diseases

1. J. Tschopp
2. G. Núñez
3. N. Inohara
4. Martin J. Blaser
5. Fabio Martinon
6. L. Franchi
7. Annick Mayor

In Small Animals

1. R. Peek
2. E. Kuipers
3. A. V. van Vliet
4. J. G. Kusters
5. B. Sinha
6. Martin J. Fraunholz

In Surgery

1. J. Tschopp
2. Martin J. Blaser
3. R. Peek
4. Stanley Falkow
5. G. Núñez
6. P. Murray
7. E. Kuipers
8. A. V. van Vliet

Citations in the corpus

• Helicobacter pylori: gastric cancer and beyond (2010, background): “, where they are sensed by an intracytoplasmic pathogen-recognition molecule nucleotide-binding oligomerization domain-containing protein 1 ( NOD1”
• The inflammasomes: guardians of the body. (2009, background): “Helicobacter pylori, for example, elicits NOD1 activation by delivering PGN fragments into the host cell through a mechanism that requires a functional type IV secretion system (64).”
• Pathogenesis of Helicobacter pylori Infection (2006, background): “pylori infection provides data that indicate that the in vitro-observed Nod1-mediated activation of the innate immune system is also important in vivo (665).”
• Signalling pathways and molecular interactions of NOD1 and NOD2 (2006, background): “Moreover, CARD4 is involved in host defence against Helicobacter pylori infection of the gastric mucosa, a chronic infection that can lead to peptic ulcers and gastric cance”
• The Microbiome in Infectious Disease and Inflammation (2012, neutral): “In vivo, NOD1 plays a critical role in the host defense against infection by Helicobacter pylori (107).”
• Function of Nod‐like receptors in microbial recognition and host defense (2009, background): “Stimulation of Nod1 or Nod2 results in the activation of NF-jB and MAPKs, which drive the transcription of numerous genes involved in both innate and adaptive immune responses (35) (Fig.”