Rhamnolipid Surfactant Production Affects Biofilm Architecture in Pseudomonas aeruginosa PAO1

By M. E. Davey, N. Caiazza, G. O’Toole. Journal of Bacteriology, 2003

818 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/ad6e50b5c19db6c8eb7dcfa50f733b4a2d79748f

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The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. T. Bjarnsholt
2. P. Watnick
3. E. Karatan
4. M. Otto
5. Bernd H. A. Rehm
6. A. Horswill
7. S. Ghods
8. J. Kaplan

In Molecular Biology

1. M. Otto
2. T. Bjarnsholt
3. J. Kaplan
4. P. Watnick
5. E. Karatan
6. M. Givskov
7. A. Horswill
8. Søren Molin

In Molecular Medicine

1. T. Bjarnsholt
2. H. Bais
3. Jorge M. Vivanco
4. R. Fall
5. Bernd H. A. Rehm
6. A. Horswill
7. P. Watnick
8. S. Ghods

Citations in the corpus

• Biofilms: the matrix revisited. (2005, background): “However, rhamnolipid production, which is under quorum-sensing control, does play a role in shaping the biofilm architecture by keeping the water channels of the biofilm open during maturation of the matrix [ 36 ].”
• Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses (2010, background): “C4-HSL may induce dispersal by up-regulation of the rhamnolipid biosynthetic gene rhaA (Davey et al., 2003).”
• Bacillus subtilis antibiotics: structures, syntheses and specific functions (2005, background): “…in other bacilli (Yan et al., 2003) or the observation that surface-active rhamnolipid surfactants affect the architecture of biofilms in Pseudomonas aerginosa (Davey et al., 2003) suggests that biofilm-associated antibiotic/surfactant production is more widely distributed than previously thought.”
• Rhamnolipids: diversity of structures, microbial origins and roles (2010, background): “…were shown to mediate the detachment and dispersion of P. aeruginosa cells from the biofilm, especially from the center of microcolonies (Boles et al. 2005; Schooling et al. 2004) and to maintain open the channels inside the biofilm during late stages of biofilm development (Davey et al. 2003).”
• A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms (2006, background): “…but with the exception of rhamnolipid, which has been shown to play a role in maintaining the channels between the mushroom-shaped structures (Davey et al., 2003), the actual quorum sensing-controlled Quorum sensing-regulated DNA release 1125 © 2005 The Authors Journal compilation © 2005…”
• Bacillus subtilis: A plant-growth promoting rhizobacterium that also impacts biotic stress (2019, background): “B. subtilis also forms biofilms on plant roots which help to produced lipopeptides and augment their antimicrobial activity in the soil (Davey et al., 2003).”
• Sociomicrobiology: the connections between quorum sensing and biofilms. (2005, neutral): “Davey and O’Toole [ 24 ] showed that rhamnolipid production was required for maintenance of architecture in structured biofilms.”
• The role of bacterial biofilms in chronic infections (2013, background): “other macromolecular components such as proteins (64–66), lipids (67), biosurfactants (68, 69), flagella and pili (70–72).”
• Cell Death in Pseudomonas aeruginosa Biofilm Development (2003, background): “A recent study demonstrated that water channels around P. aeruginosa microcolonies are actively maintained by the quorum-sensing-controlled production of rhamnolipid surfactants ( 12 ).”
• agr-Mediated Dispersal of Staphylococcus aureus Biofilms (2008, background): “Alternatively, detachment studies have addressed effector gene products that contribute to the dissolution of the biofilm, including surfactants [10,13,64,65], hydrolases [66,67], proteases [37–39], and DNase [68].”
• Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms (2009, background): “In agreement with this, more mature 6-day-old biofilms made by the rhlA mutant have flat topology (67).”