The role of bacterial biofilms in chronic infections

By T. Bjarnsholt. APMIS. Supplementum, 2013

795 citations recorded by the source corpus.

Subfields: Endocrinology, Molecular Biology, Periodontics

View Paper: https://www.semanticscholar.org/paper/cc8122c73ccc441bd2db81248d8ef6f0ea2d8463

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Citations in the corpus

Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment (2023, positive): “When c-di-GMP is degraded, clusters of the biofilm are torn apart by shear pressures or discharge planktonic cells which then dissolve parts of EPS [27,29,52].”
Beyond Risk: Bacterial Biofilms and Their Regulating Approaches (2020, background): “…et al., 2005; Rabin et al., 2015); Haemophilus influenza biofilm is among the causative agents of otitis media (Akyildiz et al., 2013; Bjarnsholt, 2013); Periodontitis, an infection of the gums that damages the soft tissues as well as bones supporting the teeth, is normally caused by…”
Antibiotic resistance and persistence—Implications for human health and treatment perspectives (2020, positive): “Chronic infections are associated with bacterial biofilms, and the newly linked phenomenon of antibiotic persistence added a novel point of view to recurring and difficult-to-treat infections and attracted the interest of more and more scientists worldwide (Bjarnsholt, 2013; Lebeaux et al , 2014).”
Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention (2018, background): “This transformation begins almost immediately after bacterial colonization of both biotic and abiotic surfaces and results in the production of a protective barrier that protects the bacteria against the organism’s endogenous defense system or from external agents such as antibiotics [1, 5, 6].”
Nano-Strategies to Fight Multidrug Resistant Bacteria—“A Battle of the Titans” (2018, background): “EPS provide a barrier allowing to inhibit the penetration of antibiotics and further promote antibiotic resistance leading to a serious health threat worldwide since biofilms are resistant to antibiotics penetration and escape innate immune system by phagocytes (Hall-Stoodley et al., 2004; Bjarnshol”
Bacterial Biofilm and its Role in the Pathogenesis of Disease (2020, background): “Since then, biofilms have been recognized to be involved in many clinical infections [2,3], and evidence is accumulating that biofilms contribute to the pathogenesis, especially in chronic infections [4].”