Neurobiology of depression.

By E. Nestler, M. Barrot, R. DiLeone, A. Eisch, S. Gold, L. Monteggia. Neuron, 2002

1,803 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/ad4eb3fd2eb629332431ef989d90d07f600355b5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects (2003, background): “These observations suggest that alterations in monoamine metabolism alone cannot explain the entire antidepressant effect (Nestler et al., 2002) and indicate that antidepressants may act by evoking adaptive changes in intracellular signal transduction and synaptic connectivity (Duman et al., 1997;…”
The mesolimbic dopamine reward circuit in depression. (2006, background): “However, while the hippocampus and frontal cortex are undoubtedly involved in aspects of depression and its treatment, it is unlikely that these regions account for all symptoms of the disorder (Nestler et al 2002).”
Epigenetic regulation in psychiatric disorders (2007, background): “, a brain region implicated in the pathophysiology and treatment of depressio”
Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. (2012, neutral): “57, 10117 Berlin, Germany. family history) and environmental influences (stress, abuse, neglect, adverse family relations) across the lifespan together likely underlie vulnerability for depression (see, for example, Kendler et al., 2002; Merikangas and Swendsen, 1997; Nestler et al., 2002).”
A review of depression and suicide risk assessment using speech analysis (2015, background): “…and connectivity - of cortical-limbic systems (Deckersbach et al., 2006; Evans et al., 2006; Mayberg et al., 2005; Niemiec and Lithgow, 2005), resulting from interactions between a genetic predisposition and environmental factors including stress and emotional trauma (Nestler et al., 2002).”
Is mood chemistry? (2005, background): “It soon became evident that the monoamine hypothesis in its original form could not explain all of the effects of antidepressant”
Adult hippocampal neurogenesis in depression (2007, background): “The heterogeneity of depression implies that multiple neural substrates and mechanisms contribute to its etiolog”
A standardized protocol for repeated social defeat stress in mice (2011, neutral): “A major obstacle in the assessment and clinical treatment of stress-related disorders is the limited availability of validated preclinical animal models to determine their underlying biological mechanism”