Is mood chemistry?

By Eero Castrén. Nature Reviews Neuroscience, 2005

606 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/3b04e6df3b803f823ab91139a360c41918d66637

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. L. Monteggia
2. T. Rantamäki
3. R. Duman
4. Keri Martinowich
5. H. Schmidt
6. Eero Castrén
7. B. Lu
8. Jaak Panksepp

In Cognitive Neuroscience

1. T. Rantamäki
2. R. Duman
3. D. Watt
4. Irene Tracey
5. Jaak Panksepp
6. B. Lu
7. P. Mantyh
8. Keri Martinowich

Citations in the corpus

• The Link between Depression and Chronic Pain: Neural Mechanisms in the Brain (2017, background): “For monoamine neurotransmitters, neurotransmitter reuptake is one of the most important determinants of signal kinetics and regulation of neurotransmitter reuptake also helps regulate the activity of the nervous network across the CNS, thus achieving an antidepressant effect [94].”
• Depression: An Evolutionarily Conserved Mechanism to Terminate Separation Distress? A Review of Aminergic, Peptidergic, and Neural Network Perspectives (2009, background): “Although the neural network perspective of depression is gaining ground (Castrén, 2005; Harro & Oreland, 2001), few have tried to consistently conceptualize depression in more coherent psychological–evolutionary terms.”
• Interaction between BDNF and Serotonin: Role in Mood Disorders (2008, background): “…clinically used antidepressants increase the extracellular concentrations of the monoamines serotonin or norepinephrine either by inhibiting their re-uptake from the synapse of by blocking their degradation by inhibiting the monoamine oxidase (Duman et al, 1997; Nestler et al, 2002; Castren, 2005).”
• The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “In this regard, antidepressant treatments restore network function and ultimately mood, in part, by increasing expression of neurotrophic factors, which promote activity-dependent neural plasticity (Castren, 2005).”
• A neurotrophic model for stress-related mood disorders. (2006, background): “It is interesting to speculate that alterations in levels of DNF and/or other factors could underlie or contribute to bnormal information processing, a recently proposed theory f depression (Castren 2005).”
• The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity (2010, background): “The clinical antidepressant response develops slowly over the first weeks of treatment and one explanation for this delayed response may be a need for physical growth and reorganization in the brain, responses which are mediated by BDNF signaling (Castrén, 2005).”
• Role of neurotrophic factors in depression. (2007, background): “Conclusions A new view of the pathophysiology of mood disorders and antidepressant drug action is emerging from research performed during the past decade [3].”
• The cerebral signature for pain perception and its modulation. (2007, background): “Central neuronal plasticity may underlie both conditions, further complicating our ability to dissect the components contributing to clinical pain disorders (Castren, 2005).”