The diverse functions of microRNAs in animal development and disease.

By Wigard P. Kloosterman, Ronald H. A. Plasterk. Developmental Cell, 2006

2,098 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ac703c06beb71198911903294cabb4737c2ead91

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Citations in the corpus

Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB (2013, background): “Small ncRNAs such as microRNAs regulate the expression of target genes at the level of translation or mRNA stability, whereas piwi-interacting RNAs (piRNA) have been linked to transcriptional gene silencing of retrotransposons and other repeat-containing genetic elements [5,6,7,8].”
Development of microRNA therapeutics is coming of age (2014, neutral): “Indeed, miRNAs have been implicated in the regulation of many cellular and developmental processes (Kloosterman & Plasterk, 2006; Bushati & Cohen, 2007; Braun & Gautel, 2011).”
Mechanisms of microRNA‐mediated gene regulation (2007, background): “[ 3 ]). In general, miRNAs function post-transcriptionally by reducing protein yield from specific target mRNAs.”
The evolution of gene regulation by transcription factors and microRNAs (2007, background): “Various studies have demonstrated that miRNAs have important roles in animal and plant development (see Ref”
miRBase: tools for microRNA genomics (2007, background): “Readers are referred to a number of comprehensive reviews of miRNA structure, biogenesis function (4,10–12).”
miR-145 and miR-143 Regulate Smooth Muscle Cell Fate Decisions (2009, methodology): “Putative miRNA target genes were identified using an in-house automated algorithm based on empirical miRNA:mRNA interaction data(7,10) that qualifies mRNAs based on (1) complementarity between the seed region of the miRNA and the mRNA 39 UTR as annotated in RefSeq; (2) identification of an extended ”
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? (2008, background): “jpg" NDATA ITEM> ]> MicroRNAs (miRNAs), which are approximately 21-nucleotide-long RNA regulators of gene expressio”
Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. (2008, background): “The miRNA control basic biologic functions, such as embryogenesis, organogenesis, proliferation, apoptosis, stress, and the antiviral response ( 8 ).”
Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation (2007, background): “…which can also be associated with transcript destabiliza- tion (Bagga et al, 2005; Giraldez et al, 2006; Wu et al, 2006). miRNAs have been found to be implicated in a large variety of cellular processes, and their aberrant expression has been linked to disease (Kloosterman and Plasterk, 2006).”