ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase.

By Z. Gong, T. Morales-Ruiz, R. R. Ariza, T. Roldán-Arjona, Lisa David, Jian-Kang Zhu. Cell, 2002

718 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ac47de6db16709286261d011fe7a775a5d806498

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In Plant Science

Citations in the corpus

Epigenetic reprogramming in mammals. (2005, background): “In plants, DNA glycosylases and presumably DNA repair are involved in overcoming silencing by methylation of imprinted genes and transgenes (115,116).”
Highly integrated single-base resolution maps of the epigenome in Arabidopsis. (2008, positive): “Furthermore, the recent characterization of the DNA demethylases ROS1, DME, DML2, and DML3 in Arabidopsis suggests that subsets of genomic DNA methylation patterns are the products of antagonistic methylation-demethylation activity (Gong et al., 2002; Penterman et al., 2007).”
DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation. (2006, background): “Another DME family member, ROS1, also has activity on 5-methylcytosine in vitro (Gong et al., 2002).”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “This protein was studied for its role in epigenetic control of gene expression (Gong et al., 2002), but it contains an endonuclease III domain with significant similarities to BER DNA proteins in the HhH-GPD superfamily (Ponferrada-Marín et al.”
Gardening the genome: DNA methylation in Arabidopsis thaliana (2005, methodology): “org/servlets/TairObject?id=1000641054&type=gene"> ROS1 ) was characterized in a screen that used a COLD REGULATED 78 ( COR78 ) promoter — LUCIFERASE transgene — as a reporte”
Epigenetic reprogramming and induced pluripotency (2009, background): “Compelling evidence indicates that DNA demethylation can occur by methylcytosine-specific DNA glycosylases and by the base excision repair machinery in plants (Choi et al., 2002; Gong et al., 2002).”