State-dependent opioid control of pain

By H. Fields. Nature Reviews Neuroscience, 2004

935 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/ac45d4416edecb91a6993b08c9826e1cec4b1681

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

In Molecular Biology

In Physiology

Citations in the corpus

Kinship, familiarity and social status modulate social learning about “micropredators” (biting flies) in deer mice (2005, background): “They serve to shift the motivational state of individuals towards the display of behaviors associated with coping with either actual or potential threats and away from the expression of nondefensive behaviors (Kavaliers and Choleris 2001; Fields 2004 ).”
Gut feelings: the emerging biology of gut–brain communication (2011, background): “Descending opioid-dependent pain modulation pathways are also engaged by other behavioural and motivational states, including vigilance and fea”
The theory of constructed emotion: an active inference account of interoception and categorization (2017, positive): “…example, ascending interoceptive signals bring sensory prediction errors from the internal milieu to the brain via lamina I and vagal afferent pathways, and they are anatomically positioned to be modulated by descending visceromotor predictions that control the internal milieu (e.g. Fields, 2004).”
Neurobiological Mechanisms of the Placebo Effect (2005, background): “The gate control theory posits and much subsequent work on central regulation of pain has shown that the periaqueductal gray (PAG) exerts central control over spinal pain pathways (Melzack and Wall, 1965; Fields, 2004).”
Beyond the connectome: How neuromodulators shape neural circuits (2012, background): “opioid receptors on the presynaptic terminals of primary nociceptive neurons and spinal cord resident neurons [38].”
A common neurobiology for pain and pleasure (2008, background): “The amygdala modulates pain perception through direct connections with the descending pain inhibitory syste”
What is reinforced by phasic dopamine signals? (2008, background): “The reinforcing consequences of terminating an aversive event are widely appreciated (Craig, 2003; Fields, 2004; Kim et al., 2006; Seymour et al., 2005).”
A comprehensive review of the placebo effect: recent advances and current thought. (2008, background): “They also have found that these reductions are accompanied by increases in neural activity within brain areas known to be involved in emotional regulation (Fields 2004, Petrovic et al. 2005, Zubieta et al. 2001).”
Pathophysiology of Migraine: A Disorder of Sensory Processing. (2017, background): “There is also thought to be state-dependent and bidirectional control of pain modulation through serotonergic projections from the RVM to the TCC that is distinct to “ON” and “OFF” cells (269).”