Real-time kinetics of gene activity in individual bacteria.

By I. Golding, Johan Paulsson, Scott M. Zawilski, E. Cox. Cell, 2005

1,518 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ab7dd811be154081aa8c7e778a0ecde7fbac17a8

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Citations in the corpus

Estimating accuracy of RNA-Seq and microarrays with proteomics (2009, neutral): “5 [6,22-27], thus indicating that mRNA and protein expression levels are not fully independent.”
Modelling and analysis of gene regulatory networks (2008, background): “Recently, single-cell experimental assays demonstrated the stochastic behaviour of the processes of transcriptio”
Phenotypic consequences of promoter-mediated transcriptional noise. (2006, background): “…the biochemical processes of transcription and translation (Ozbudak et al., 2002; Elowitz et al., 2002; Blake et al., 2003; Raser and O'Shea, 2004; Golding et al., 2005), the remodeling of chromatin (Blake et al., 2003; Raser and O'Shea, 2004; Sato et al., 2004), the partitioning of proteins…”
SINGLE-PARTICLE TRACKING (2009, neutral): “tistical noise [24–27].”
Single-RNA counting reveals alternative modes of gene expression in yeast (2008, background): “Transcriptional bursting has also been observed in bacteria, although in this system bursting was much weaker and measured only on an inducible gen”
Correlation of mRNA and protein in complex biological samples (2009, positive): “This ability to measure has provided important details of how transcription is carried out in pulses [10–12].”
Analytical distributions for stochastic gene expression (2008, background): “Such transitions could be from changes in chromatin structure, from binding and unbinding of proteins involved in transcription [3, 4, 12], or from pausing by RNA polymerase [18].”
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. (2007, background): “The eukaryotic cell is a noisy environment in which transcription often occurs in a bursting manner (Blake et al., 2006; Golding et al., 2005; Raj et al., 2006), causing the number of mRNAs per cell— which can go as low as fractions of a copy when averaged over a population—to fluctuate significantl”
Introduction to systems biology. (2007, background): “One successful approach of synthetic biology has been the analysis of noise [104–111].”