Biotechnological Production of Lactic Acid and Its Recent Applications

By Y. Wee, Jin-nam Kim, H. Ryu. 2006

644 citations recorded by the source corpus.

Summary Lactic acid is widely used in the food, cosmetic, pharmaceutical, and chemical industries and has received increased attention for use as a monomer for the production of biodegradable poly(lactic acid). It can be produced by either biotechnological fermentation or chemical synthesis, but the former route has received considerable interest recently, due to environmental concerns and the limited nature of petrochemical feedstocks. There have been various attempts to produce lactic acid efficiently from inexpensive raw materials. We present a review of lactic acid-producing microorganisms, raw materials for lactic acid production, fermentation approaches for lactic acid production, and various applications of lactic acid, with a particular focus on recent investigations. In addition, the future potentials and economic impacts of lactic acid are discussed.

View Paper: https://www.semanticscholar.org/paper/ab16ad6643e6a32da14cd98358df6af5a09f110c

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Citations in the corpus

• Enhanced volatile fatty acids production from anaerobic fermentation of food waste: A mini-review focusing on acidogenic metabolic pathways. (2018, unknown): “Lactic acid has been widely used in the food, pharmaceutical, and cosmetic industries and also as a useful monomer for the production of biodegradable polymers in chemical industry (Wee et al., 2006).”
• Modern Biotechnological Polymer Synthesis: A Review (2010, background): “The optical purity of lactic acid is crucial to the physical properties of PLA, and an optically pure L(+)- or D(–)-lactic acid, rather than racemic DL-lactic acid, can be polymerized to a high crystalline PLA, which is suitable for commercial uses (39).”
• An overview of the recent developments in polylactide (PLA) research. (2010, background): “The major manufacturers of fermentative lactic acid include Natureworks LLC, Purac (Netherlands), Galactic (Belgium), Cargill (USA), and several Chinese companies (Wee et al., 2006).”
• Photocatalytic conversion of biomass-based monosaccharides to lactic acid by ultrathin porous oxygen doped carbon nitride (2021, background): “[18] Lactic acid can be used as precursors to prepare biodegradable polymers (polylactic acid) [19] and other commodity chemicals [20-22] (e.”
• Lactic Acid Bacteria Antimicrobial Compounds: Characteristics and Applications (2012, background): “It eventually influences the trans-membrane pH gradient and decreases the amount of available energy for cells to grow [114, 154].”