Homeostasis of naive and memory T cells.

By C. Surh, J. Sprent. Immunity, 2008

1,265 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/aa1b2271a4a78624ca7b1a63bea416832337fe69

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Citations in the corpus

Overcoming T cell exhaustion in infection and cancer (2015, background): “A cardinal feature of functional CD8+ TMEM cells is IL-7- and IL-15-driven, antigen-independent proliferation that allows these cells to persist long after antigen has been eliminated [48].”
Anti- and Pro-inflammatory Roles of TGF-β, IL-10, and IL-22 In Immunity and Autoimmunity (2009, background): “However, positively selected thymocytes also retain some self-reactivity, which is essential for survival of naı̈ve T cells that requires TCR signaling and cytokines such as IL-7 [8].”
Mitochondrial Respiratory Capacity Is A Critical Regulator Of CD8+ T Cell Memory Development (2011, background): “We investigated whether the cytokines IL-2 and IL-15, which are critical for the development and maintenance of CD8 Teff cells and memory T cells, respectively (Kennedy et al., 2000; Mitchell et al., 2010; Sandau et al., 2010; Schluns et al., 2002; Surh and Sprent, 2008; Tan et al., 2002; Zhang et a”
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer. (2019, background): “Tmem cells downregulate their effector program and acquire a stem cell–like ability to survive, independent of antigen, as long-lived cells that undergo slow homeostatic self-renewal driven by IL-7 and IL-15 (6).”
Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets (2012, positive): “Alternately, differences in homeostatic turnover between CD4 and CD8 T cells could contribute to differences in memory accumulation, as shown by the fact that phenotypic conversion of mouse and human naive T cells to memory cells can occur because of homeostatic expansion independent of effector dif”
New insights into the regulation of T cells by γc family cytokines (2009, neutral): “In addition, IL-7 is well known for its potent role as a lymphocyte survival facto”
CD28− T cells: their role in the age-associated decline of immune function (2009, background): “IL-7 and IL-15 are critically important for the homeostatic maintenance of T cells in the absence of antigenic stimulation, particularly for CD8 memory T cells [30].”
From Vaccines to Memory and Back (2010, positive): “For CD4 and CD8 memory T cells the survival cytokines are IL-7 and IL-15 which maintain these cells in a state of slow but continuous proliferation (Surh and Sprent, 2008).”
mTOR regulates memory CD8 T cell differentiation (2009, neutral): “Three different treatment periods were used: (1) throughout LCMV infection (day 21 before infection to the memory phase, day 35 post-infection); (2) the T-cell expansion phase (day 21 before infection to day 8 post-infection); or (3) T-cell contraction phase (day 8 to the memory phase, day 35 post-i”
Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis (2010, background): “In a chronically lymphopenic Rag2 / mouse, commensal bacteria and selfantigens along with cytokines drive the initial rapid expansion of naive T cells (Surh and Sprent, 2008).”
Tissue-Resident Memory T Cells (2014, background): “Similarly, dendritic cells upregulate CCR7 after activation in tissues, which then acts in concert with S1PR1 to promote migration to downstream SLOs (Braun et al., 2011; Czeloth et al., 2005; Lamana et al., 2011; Ohl et al., 2004; Saeki et al., 1999).”