Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.

By Jian-Mei Li, A. Shah. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2004

799 citations recorded by the source corpus.

Subfields: Biochemistry, Immunology, Physiology

View Paper: https://www.semanticscholar.org/paper/a8c439b9fdd28dcee75549ec6a0e71220383dba7

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Citations in the corpus

Mitochondrial dysfunction and molecular pathways of disease. (2007, background): “TNF-α and NF-κB are important pro-inflammatory mediators, along with ROS, in many diseases, such as rheumatoid arthritis (Makarov, 2001), cardiovascular disease (Li and Shah, 2004), and renal fibrosis (Klahr and Morrissey, 2002).”
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production (2008, background): “The enzyme contains four of the subunits that are found in the enzyme in phagocytic cells (gp91, p22, p47, and p67), all of which were associated with the cell membranes (236).”
Oxidant Mechanisms in Renal Injury and Disease (2016, positive): “This adverse effect on the endothelium promotes inﬂammation, including enhanced cytokine production and expression of surface adhesion molecules (160) effectively promoting vascular remodeling.”
Endothelial dysfunction - a major mediator of diabetic vascular disease. (2013, background): “Glutathione is the principal low molecular weight, non-protein thiol in the cell [140].”
Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy. (2008, background): “Protein kinase C isoforms are the major kinases responsible for p47 phosphorylation although other kinases such as Akt, p38 MAP kinase and PAK (p21-activated kinase) also play a role depending on the stimulus [59,98,99].”
Hydrogen Peroxide: A Signaling Messenger (2006, neutral): “Over the last 10 years it has become clear that numerous diverse stimuli stimulate mammalian cells to release O2 and/or H2O2, including growth factors, cytokines, vasoactive modulators, integrins, and biomechanical stimulation (126, 193, 205).”
Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities (2011, neutral): “1) (222, 338).”
Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol (2006, background): “It has clearly been established that the endothelial dysfunction associated with these disorders is related to the local formation of reactive oxygen and nitrogen species in the vicinity of the vascular endothelium (overview in Li and Shah, 2004).”