Hydrogen Peroxide: A Signaling Messenger

By James R. Stone, Suping Yang. Antioxidants and Redox Signaling, 2006

1,160 citations recorded by the source corpus.

Subfields: Environmental Chemistry, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/d27ecd4026245359bffb0b90ab0ad281dd7e15da

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Environmental Chemistry

1. C. Gentry
2. S. Bevan
3. D. Gupta
4. D. Andersson
5. Sian Moss
6. C. Winterbourn
7. Michael R Hamblin
8. H. Sies

In Molecular Biology

1. James J. Collins
2. Ahmad S. Khalil
3. Michael R Hamblin
4. K. Allison
5. Daniel J. Dwyer
6. C. Winterbourn
7. C. Gentry
8. S. Bevan

In Physiology

1. C. Gentry
2. S. Bevan
3. James J. Collins
4. S. Rhee
5. D. Andersson
6. Sian Moss
7. C. Winterbourn
8. Michael R Hamblin

Citations in the corpus

• Essential oils of catmint (Nepeta meyeri Benth.) induce oxidative stress in early seedlings of various weed species (2011, background): “At low concentrations, it aids in cellular defense, and provides tolerance against stress, whereas at high concentrations, it induces cellular damage (Stone and Yang 2006).”
• Redox Regulation in Photosynthetic Organisms: Signaling, Acclimation, and Practical Implications (2009, neutral): “While a relatively large number of genes have been identified as singlet oxygen-inducible (11, 236, 307), the mechanism of signal transduction is unknown.”
• Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation (2018, background): “peroxide by MnSOD, then the uncharged H2O2 is free to diffuse outside the mitochondria where it can take part in many signaling pathways (55).”
• Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress☆ (2017, background): “which is 10-fold higher than previous estimations [5].”
• Redox regulation of FoxO transcription factors (2015, background): “In contrast, application of exogenous H2O2 in higher micromolar concentrations initially induces growth arrest and possibly a subsequent cellular adaptation to oxidative stress [119].”
• Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress (2008, positive): “The intracellular H 2 O 2 concentration is probably 7 – 10 times lower than the extracellularly applied concentration ( Stone and Yang , 2006 ) , suggesting that TRPA1 can be activated when the intracellular H 2 O 2 concentration reaches tens of micromolar .”
• Antioxidants and Antioxidant Enzymes in Higher Plants (2018, background): “High H2O2 concentrations are potentially deleterious for cells for the reason described above; however, at low levels, hydrogen peroxide acts as an intramolecular messenger in cellular signalling (Neill et al. 2002; Vivancos et al. 2005; Stone and Yang 2006; Veal et al. 2007).”