Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
By Shimon Sakaguchi, M. Ono, Ruka Setoguchi, H. Yagi, S. Hori, Z. Fehérvári, J. Shimizu, Takeshi Takahashi, T. Nomura. Immunological Reviews, 2006
1,669 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/a87b7aa5a38fa4f77a8f8fc9b4b3a6c6a188967a
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In Immunology
- Jacques Banchereau
- Atsushi Tanaka
- Shimon Sakaguchi
- Naganari Ohkura
- J. Wing
- A. Palucka
- K. Ichiyama
- N. Mikami
Citations in the corpus
- CD4+T Cells: Differentiation and Functions (2012, background): “After clearance of pathogens, they negatively regulate the immune response, thereby protecting against immunopathology [32, 146].”
- Foxp3 instability leads to the generation of pathogenic memory T cells in vivo (2009, neutral): “The paradigm in immunology is that autoimmunity is precipitated by an imbalance of pathogenic T cells and Foxp3 + T reg cell”
- Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis (2010, background): “Tregs provide a primary mechanism to suppress aberrant immune responses and promote protection from inflammatory disease (21).”
- Regulatory T Cells and Human Disease. (2020, background): “Further, in active immune responses, IL-2 produced by activated T cells expands Tregs, stabilizes FoxP3 expression, and enhances their suppressive activity in a negative-feedback manner (66).”
- Inflammatory mechanisms in ischemic stroke: role of inflammatory cells (2010, neutral): “diseases [91–93].”
- Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. (2008, background): “…is particularly complex because it includes T helper (Th) 1, Th2, Th17 (Weaver et al., 2007), and follicular helper T (Tfh) cells (King et al., 2008) that arise by polarized differentiation of naive precursors, as well as regulatory T (Treg) cells (Sakaguchi et al., 2006; Shevach, 2006).”
- Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke (2009, background): “Thymus-derived CD4 + CD25 + Foxp3 + T reg cells play a key part in controlling immune responses under physiological conditions and in various systemic and central nervous system inflammatory disease”