Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy

By D. Baksh, L. Song, Rocky S. Tuan. Journal of Cellular and Molecular Medicine, 2004

1,152 citations recorded by the source corpus.

Subfields: Biomaterials, Genetics, Surgery

View Paper: https://www.semanticscholar.org/paper/a7c79704026b197ebb4d8623679c82ac729d7d59

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. Elizabeth Cho
2. Catherine M. Kolf
3. Rocky S. Tuan

In Genetics

1. Rocky S. Tuan
2. Elizabeth Cho
3. Catherine M. Kolf
4. G. T. Huang
5. S. Shi
6. S. Gronthos
7. I. Sekiya
8. H. Koga

In Surgery

1. Elizabeth Cho
2. Catherine M. Kolf
3. M. Schwartz
4. Rocky S. Tuan

Citations in the corpus

• Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation (2007, positive): “Expression markers associated with chondrogenesis have been positively characterized in MSC-derived chondrocytes, including transcription factors (sox-9, scleraxis) and extracellular matrix (ECM) genes (collagen types II and IX, aggrecan, biglycan, decorin, and cartilage oligomeric matrix protein) [”
• A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow (2009, background): “MSCs are considered to be a potential source for cell and gene therapy strategie”
• Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC (2011, background): “Baksh et al compared umbilical cord perivascular cells (UCPVC) to BM-MSC and determined that the UCPVCs also have a higher proliferation capacity than the BM-MSC [45].”
• Integrins and extracellular matrix in mechanotransduction. (2010, background): “Adult mesenchymal stem cells are pluripotent progenitor/stem cells and can be differentiated into chondrocytes, tendonocytes, adipocytes, and osteoblasts.(63) Coating of engineered bioimplants with ECM, such as f ibronectin fragments, can enhance integrin-mediated adhesion in vitro, osteogenic signa”
• Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources: Their Biology and Role in Regenerative Medicine (2009, background): “The first 4 cell types are considered the essential lineages for defining multipotent MSCs (Tuli et al., 2003; Baksh et al., 2004).”
• Aging of mesenchymal stem cells. (2006, neutral): “…‘‘stromal (stem) cells’’, ‘‘bone marrow (stromal) cells’’, ‘‘skeletal stem cells’’, ‘‘mesodermal progenitor cells’’, ‘‘non-haematopoietic stem cells’’, ‘‘(bone marrow) stem cells’’, ‘‘mesenchymal progenitor cells’’ and others (see Baksh et al., 2004; Young and Black, 2004 for enumeration).”
• Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle (2007, background): “Although the precise identity of MSCs remains a challenge (Baksh et al. 2004), we define herein an MSC as being derived from mesenchymal tissue and by its functional capacity both to selfrenew and to generate a number of differentiated progeny (McKay 1997).”