The SR protein family of splicing factors: master regulators of gene expression.

By J. C. Long, J. Cáceres. Biochemical Journal, 2009

1,132 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/a77d0013d0147eb8fa2c4228c466d667dafe249a

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Citations in the corpus

Functional consequences of developmentally regulated alternative splicing (2011, background): “Loss of aurora kinase A promoted post-translational degradation of serine/arginine-rich splicing factor 1 (SRSF1), a member of the SR protein family of splicing regulator”
Rapid report Extensive coupling of alternative splicing of pre-mRNAs of serine⁄arginine (SR) genes with nonsense-mediated decay (2009, background): “Other animal and plant SRs are also known to regulate the splicing of their own transcripts and other SR gene transcripts (Reddy, 2007; Long & Caceres, 2009).”
Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches (2009, background): “ESEs are usually bound by members of the SR (Ser–Arg) protein family”
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. (2013, background): “MALAT1 might regulate alternative splicing of a subset of pre-mRNAs by modulating serine/ arginine splicing factor activity (22), which regulates tissueor cell-type–specific alternative splicing in a phosphorylationdependentmanner (23).”
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation (2010, background): “…by trans-acting protein factors, which include the small nuclear ribonucleoproteins (snRNPs), the serine/arginine-rich (SR) family of nuclear phosphoproteins (SR proteins), SR-related proteins, and the heterogeneous nuclear ribonucleoproteins (hnRNPs) (Blencowe, 2006; Long and Caceres, 2009).”
Complexity of the Alternative Splicing Landscape in Plants[C][W][OPEN] (2013, background): “…binding, transcription elongation, subcellular localization of transcripts, genome stability and formation of cellular RNA granules, and miRNA processing structures (stress granules and processing bodies) (Long and Caceres, 2009; Shepard andHertel, 2009;Rissoet al., 2012; Yoon et al., 2013).”
Abscisic Acid and Abiotic Stress Tolerance in Crop Plants (2016, background): “Besides hnRNPs, another class of RNA-binding proteins playing a key role in regulating alternative splicing is serine/arginine-rich (SR) proteins (Long and Caceres, 2009).”
Epigenetics in alternative pre-mRNA splicing (2011, neutral): “…isolated or in clusters, and stimulate (enhancers) or inhibit (silencers) the use of splice sites through the specific binding of regulatory proteins such as SR proteins (serine/arginine-rich proteins) or heterogeneous nuclear ribonucleoproteins (hnRNPs) (Long and Caceres, 2009; Han et al., 2010).”