Antibiotic resistance of bacteria in biofilms.

By Philip S. Stewart, W. Costerton. The Lancet, 2001

1,472 citations recorded by the source corpus.

Subfields: Endocrinology, Molecular Biology, Periodontics

View Paper: https://www.semanticscholar.org/paper/a555ca5cd51aa6a7e46ab0188780b9076852a14d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology

1. P. Stoodley
2. L. Hall-Stoodley
3. J. Kaplan

In Molecular Biology

1. L. Hall-Stoodley
2. P. Stoodley
3. J. Kaplan

In Periodontics

1. L. Hall-Stoodley
2. P. Stoodley

Citations in the corpus

• Multi-species biofilms: living with friendly neighbors. (2012, neutral): “This phenomenon is observed in the lungs of CF patients, which are often colonized by several bacterial species that reside in biofilms and cause persistent infections (Stewart & Costerton, 2001; Bittar et al., 2008; Armougom et al., 2009).”
• Contributions of Antibiotic Penetration, Oxygen Limitation, and Low Metabolic Activity to Tolerance of Pseudomonas aeruginosa Biofilms to Ciprofloxacin and Tobramycin (2003, neutral): “The protection of bacteria growing in biofilms from antibiotics probably depends on multiple factors (3, 19, 27, 28).”
• Horizontal Gene Exchange in Environmental Microbiota (2011, neutral): “…July 2011 | Volume 2 | Article 158 | 7 formation is linked to the pathology of many infectious diseases, and biofilms are notoriously difficult to eradicate because of the increased level of resistance to antibiotics (Stewart and Costerton, 2001; Anderson and O’Toole, 2008; Høiby et al., 2010a).”
• The role of bacterial biofilms in chronic infections (2013, neutral): “disabled ability of the phagocytes in killing the biofilm bacteria, a phenomenon termed ‘frustrated phagocytosis’ (126, 127).”
• Identification of FleQ from Pseudomonas aeruginosa as a c-di-GMP-responsive transcription factor (2008, neutral): “Biofilm infections are difficult to treat because bacteria in biofilms tend to be highly resistant to antimicrobial treatment and are able to more easily evade immune responses than planktonic cells (Stewart and Costerton, 2001; Hoiby, 2002).”
• Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics (2014, neutral): “It is now clear that well-studied mechanisms involved in classical antibiotic resistance, such as efflux or antibiotic-modifying enzymes, play only a marginal role in the ability of biofilms to survive antibiotics (20, 21).”
• Evolving concepts in biofilm infections (2009, positive): “contribute to a generalized resistance or tolerance to antibiotics (Brown et al., 1988; Anwar et al., 1992; Stewart and Costerton, 2001; Borriello et al., 2004; 2006; Shah et al., 2006).”
• Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media. (2006, neutral): “The finding that biofilms are present in almost all cases of OME in this study may help to explain the lack of antibiotic efficacy for this disorder, given that biofilm bacteria are more antibiotic resistant than single cells in suspension.(23-28) This resistance may stem from the fact that oxygen a”
• Ionic Liquids: Applications and Perspectives (2011, neutral): “A general characteristic of biofilm communities is that they tend to exhibit significant tolerance/resistance to antibiotics and antimicrobial/biocidal challenge compared with planktonic bacteria of the same species (Ceri et al., 1999; Stewart & Costerton, 2001; Gilbert et al., 2002; Stewart, 2002).”