Embryonic stem cell-specific MicroRNAs.

By Hristo B. Houbaviy, M. Murray, Phillip A. Sharp. Developmental Cell, 2003

1,139 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a4e097d41252b219d94784d687b9c4a0740e44e4

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Citations in the corpus

microRNAs as oncogenes and tumor suppressors. (2007, background): “, 2000), stem cell division (Cheng et al., 2005b; Hatfield et al., 2005; Houbaviy et al., 2003; Suh et al., 2004; Zhang et al., 2006f), apoptosis (Cheng et al.”
The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation (2006, background): “In lower organisms, miRNAs are essential for cell differentiation during developmen”
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. (2004, background): “In the past 2 years, several hundred novel genes were identified in plants (Llave et al. 2002a; Mette et al. 2002; Park et al. 2002; Reinhart et al. 2002; Palatnik et al. 2003) and animals (Lee et al. 1993; Reinhart et al. 2000; Lagos-Quintana et al. 2001, 2002, 2003; Lau et al. 2001; Lee and Ambros”
MicroRNA-155 Is Regulated by the Transforming Growth Factor β/Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA (2008, background): “Like conventional protein-encoding mRNA, miRNAs are transcribed by RNA polymerase II and controlled by transcription factors (1, 9, 16 , 38).”
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. (2007, background): “www.aacrjournals.org 6095 Cancer Res 2007; 67: ( 13 ).”
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment (2008, neutral): “dtd" [ ]> miRNA populations, including mammalian homologues of lin-4 (mir-125) and let-7, undergo a marked transition during stem-cell differentiatio”
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. (2005, methodology): “During ES cell differentiation, the miRNA expression profile changes (Houbaviy et al. 2003), and one or more newly expressed miRNAs could be involved in the regulation of transcription factors critical for cellular differentiation.”
The functions of animal microRNAs (2004, background): “For example, a set of six clustered mouse miRNAs ( miR-290 to miR-295 ) are expressed specifically in embryonic stem (ES) cell”
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. (2008, neutral): “Although ES cell-specific miRNAs have been described (Houbaviy et al., 2003), the function or potential of specific miRNAs in ES cell differentiation has not been reported.”
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (2008, background): “Further, of the additional differential miRNAs reported here (Table 1), many were originally discovered in human or murine ESCs (Houbaviy et al. 2003; Suh et al. 2004).”
Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction (2015, background): “in ESCs and forms 70% of the known miRNAs produced by ESCs.(27,28) Furthermore, members of the miR-290 family are Figure 5.”
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal (2007, background): “miR-130 is independently transcribed and expressed broadly in ES cells and differentiated tissue”