Epidermal Viral Immunity Induced by CD8α+ Dendritic Cells But Not by Langerhans Cells
By R. Allan, Chris M. Smith, G. Belz, Allison L van Lint, L. Wakim, W. Heath, F. Carbone. Science, 2003
668 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/a28bb24227bb110988b957475741203f8dfcd774
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In Immunology
- Jacques Banchereau
- Shizuo Akira
- J. Tschopp
- K. Shortman
- J. Villadangos
- A. Palucka
- Frank O. Nestle
- P. Di Meglio
In Molecular Biology
- Jüergen Cox
- Matthias Mann
- Shizuo Akira
- Christian A. Luber
- Matthias Selbach
- J. Tschopp
- Jacques Banchereau
- Stefka Tyanova
Citations in the corpus
- Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. (2005, background): “…mouse models in which infection with herpes simplex virus is confined to vaginal or epidermal epithelia, it has been reported that non-LC-derived DCs are necessary for in vivo generation of viral-specific effector T cells (Allan et al., 2003; Belz et al., 2004; Iwasaki, 2003; Zhao et al., 2003).”
- Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens (2004, background): “There is some evidence that CD8a may be upregulated a little on Langerhans’ cells as they move to the draining lymph node (LN), but this level is minimal and much lower than on CD8 DC (77).”
- Quantitative proteomics reveals subset-specific viral recognition in dendritic cells. (2010, background): “The direct and cross-presentation capabilities of CD8a+ cDCs are important in the course of viral infection (Allan et al., 2003).”
- Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming. (2006, methodology): “These results reinforce our earlier observation that class I-restricted presentation after skin infection with HSV predominantly resides with the CD8 DC population (Allan et al., 2003) and further show that these DCs are lymph node resident.”
- Skin immune sentinels in health and disease (2009, background): “may be the key APC population involved in mounting an immune respons”